Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.52 |
| ▸ | LTA4H | P09960 | 3/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133289 | 0.80 | MGAM (0.47) | LTA4HSMN1; SMN2MAPTNPSR1POLB | |
| SCHEMBL3903078 | 0.78 | LTA4H (0.38) | LTA4HSMN1; SMN2MAPTTP53POLB | |
| SCHEMBL3905440 | 0.76 | HIF1A (0.40) | SMN1; SMN2MAPTTP53POLBGAA | |
| SCHEMBL7040229 | 0.74 | LTA4H (0.57) | TAAR1LTA4HHTR1DHTR1BHTR2A | |
| SCHEMBL3907483 | 0.73 | TAAR1 (0.52) | TAAR1HTR2ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL27760631 | 0.73 | HTR1D (0.40) | TAAR1LTA4HHTR1DHTR1BMAPT | |
| SCHEMBL6371894 | 0.73 | CD44 (0.45) | LTA4HSMN1; SMN2MAPTPOLBTDP1 | |
| SCHEMBL11869781 | 0.72 | ALDH1A1 (0.47) | LTA4HSMN1; SMN2MAPTPOLBTDP1 | |
| SCHEMBL3907346 | 0.71 | TAAR1 (0.53) | TAAR1HTR2ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL28222648 | 0.71 | LTA4H (0.57) | LTA4HSMN1; SMN2MAPTTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |