Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18848272 | 0.83 | ALDH1A1 (0.53) | PAMALDH1A1MAPK1L3MBTL1CASP1 | |
| SCHEMBL126974 | 0.80 | HTT (0.66) | ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL11783251 | 0.80 | HTT (0.66) | ALDH1A1HTTLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8688569 | 0.78 | HTT (0.64) | ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL18848230 | 0.77 | ALDH1A1 (0.46) | PAMALDH1A1MAPK1L3MBTL1CASP1 | |
| SCHEMBL392909 | 0.76 | KLK7 (0.48) | ALDH1A1L3MBTL1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL18848372 | 0.76 | ALDH1A1 (0.45) | PAMALDH1A1MAPK1L3MBTL1CASP1 | |
| SCHEMBL27418764 | 0.75 | ALDH1A1 (0.77) | PAMALDH1A1MAPK1L3MBTL1AKR1B1 | |
| Glycine SCHEMBL8366779 | 0.74 | HTT (0.59) | ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL30440860 | 0.74 | ALDH1A1 (0.60) | ALDH1A1MAPK1HTTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101590-B2 | 9-aminocarbonylsubstituted derivatives of glycylcyclines | WYETH LLC (US) | 2012-01-24 | — | — | US | disclosed |
| US-20070049564-A1 | 9-Aminocarbonylsubstituted derivatives of glycylcyclines | WYETH (US) | 2007-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049564-A1 | 9-Aminocarbonylsubstituted derivatives of glycylcyclines | Q6ZSR9, GMPS, RPS10 | PAM 581/4885ALDH1A1 1826/4885MAPK1 1988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.