Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triaziquone SCHEMBL8611240 | 0.94 | — | — | |
| Triaziquone SCHEMBL3859202 | 0.94 | — | — | |
| Triaziquone SCHEMBL10698252 | 0.86 | DNMT1 (0.33) | DNMT1TP53MAPTSTAT3HTT | |
| Triaziquone SCHEMBL6629970 | 0.85 | DNMT1 (0.34) | DNMT1TP53MAPTSTAT3HTT | |
| Triaziquone SCHEMBL1892343 | 0.82 | DNMT1 (0.39) | DNMT1TP53MAPTSTAT3HTT | |
| Triaziquone SCHEMBL22346328 | 0.82 | DNMT1 (0.39) | DNMT1TP53MAPTSTAT3HTT | |
| Triaziquone SCHEMBL4299467 | 0.79 | DNMT1 (0.39) | DNMT1TP53MAPTSTAT3HTT | |
| Triaziquone SCHEMBL7613231 | 0.79 | DNMT1 (0.39) | DNMT1MAPTHTTSMN1; SMN2 | |
| Triaziquone SCHEMBL7803524 | 0.79 | DNMT1 (0.36) | DNMT1TP53MAPTSTAT3HTT | |
| Triaziquone SCHEMBL983045 | 0.78 | DNMT1 (0.38) | DNMT1TP53MAPTSTAT3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664273-A4 | ARRAYS, METHODS AND KITS FOR PREPARATION AND USE OF SYNTENIC GENOMIC ARRAYS FOR DIAGNOSTICS AND TOXICOLOGY | PERKINELMER LAS INC (US) | 2009-04-01 | — | — | EP | disclosed |
| EP-1664273-A2 | ARRAYS, METHODS AND KITS FOR PREPARATION AND USE OF SYNTENIC GENOMIC ARRAYS FOR DIAGNOSTICS AND TOXICOLOGY | Spectral Genomics, Inc (US) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005012500-A2 | ARRAYS, METHODS AND KITS FOR PREPARATION AND USE OF SYNTENIC GENOMIC ARRAYS FOR DIAGNOSTICS AND TOXICOLOGY | SPECTRAL GENOMICS, INC. (US) | 2005-02-10 | — | — | WO | disclosed |