Triaziquone

Triaziquone

SCHEMBL10698252

O=C(O)CNC(O)(O)O.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1

nearest known ligand 0.33

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.33
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.32
STAT3 P40763 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NSD2 O96028 1/20 0.31
TTR P02766 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL3300089 0.88 DNMT1 (0.35) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL3903404 0.86 DNMT1 (0.32) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL1892343 0.85 DNMT1 (0.39) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL3421294 0.84 MAPT (0.36) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL6629970 0.84 DNMT1 (0.34) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL4299467 0.82 DNMT1 (0.39) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL22346328 0.82 DNMT1 (0.39) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL4608905 0.81 DNMT1 (0.43) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL3859202 0.81
Triaziquone SCHEMBL8611240 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0279273-A2 DNA sequences, plasmids, microorganisms and process for producing quinolin acid RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) 1988-08-24 EP disclosed