Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | LAP3 | P28838 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56898 | 1.00 | FDPS (0.48) | FDPSKDM4EMMP2THRBMAPK1 | |
| Water SCHEMBL30541817 | 0.97 | FDPS (0.46) | FDPSKDM4EMMP2THRBMAPK1 | |
| SCHEMBL30607730 | 0.97 | FDPS (0.46) | FDPSKDM4EMMP2THRBMAPK1 | |
| SCHEMBL28378469 | 0.97 | FDPS (0.46) | FDPSKDM4EMMP2THRBMAPK1 | |
| Ammonia Solution, Strong SCHEMBL1478027 | 0.97 | FDPS (0.46) | FDPSKDM4EMMP2THRBMAPK1 | |
| SCHEMBL1877265 | 0.97 | FDPS (0.46) | FDPSKDM4EMMP2THRBMAPK1 | |
| SCHEMBL31304816 | 0.97 | FDPS (0.46) | FDPSKDM4EMMP2THRBMAPK1 | |
| SCHEMBL10619694 | 0.97 | FDPS (0.46) | FDPSKDM4EMMP2THRBMAPK1 | |
| SCHEMBL32670822 | 0.97 | FDPS (0.46) | FDPSKDM4EMMP2THRBMAPK1 | |
| SCHEMBL31122734 | 0.97 | FDPS (0.46) | FDPSKDM4EMMP2THRBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539345-A4 | CALCIUM HYDROXIDE ABSORBENT WITH RHEOLOGY MODIFIER AND PROCESS INVOLVING SAME | GRACE W R & CO (US) | 2009-01-28 | — | — | EP | claimed |
| EP-1539345-A2 | CALCIUM HYDROXIDE ABSORBENT WITH RHEOLOGY MODIFIER AND PROCESS INVOLVING SAME | W.R. Grace & Co. (US) | 2005-06-15 | — | — | EP | claimed |
| WO-2004022641-A2 | CALCIUM HYDROXIDE ABSORBENT WITH RHEOLOGY MODIFIER AND PROCESS INVOLVING SAME | W.R. GRACE & CO.-CONN (US) | 2004-03-18 | — | — | WO | claimed |