Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 10/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14415627 | 0.90 | ADRA2C (0.50) | ADRA2CTAAR1HTR7DPP4PTGER1 | |
| SCHEMBL16814898 | 0.86 | DPP4 (0.62) | ADRA2CTAAR1DPP4PTGER1PTGER4 | |
| Hydrochloric Acid SCHEMBL4750273 | 0.84 | TAAR1 (0.52) | ADRA2CTAAR1DPP4CD274 | |
| SCHEMBL19910795 | 0.81 | TAAR1 (0.50) | ADRA2CTAAR1HTR7PTGER2 | |
| SCHEMBL16520425 | 0.81 | TAAR1 (0.50) | ADRA2CTAAR1HTR7PTGER2 | |
| SCHEMBL3904438 | 0.80 | TAAR1 (0.55) | ADRA2CTAAR1DPP4 | |
| SCHEMBL11994129 | 0.80 | MC4R (0.47) | ADRA2CTAAR1HTR7PTGER1PTGER4 | |
| SCHEMBL7710601 | 0.79 | ADRA2C (0.60) | ADRA2CTAAR1HTR7DPP4PTGER1 | |
| SCHEMBL1868872 | 0.79 | DPP4 (0.68) | ADRA2CTAAR1DPP4 | |
| SCHEMBL26823954 | 0.79 | TAAR1 (0.51) | ADRA2CTAAR1HTR7CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |