Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 12/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30066159 | 0.98 | S1PR1 (0.41) | S1PR1S1PR3S1PR4S1PR5ADORA3 | |
| SCHEMBL932498 | 0.98 | S1PR1 (0.41) | S1PR1S1PR3S1PR4S1PR5ADORA3 | |
| SCHEMBL3897505 | 0.95 | NOTUM (0.40) | S1PR1S1PR3S1PR4S1PR5ADORA3 | |
| SCHEMBL31435310 | 0.95 | NOTUM (0.40) | S1PR1S1PR3S1PR4S1PR5ADORA3 | |
| SCHEMBL3901815 | 0.92 | NOTUM (0.44) | S1PR1S1PR3S1PR4S1PR5NOTUM | |
| SCHEMBL2231906 | 0.86 | NOTUM (0.40) | S1PR1S1PR3NOTUM | |
| SCHEMBL2235318 | 0.85 | S1PR1 (0.43) | S1PR1S1PR3S1PR4S1PR5ADORA3 | |
| SCHEMBL3846473 | 0.84 | S1PR1 (0.44) | S1PR1S1PR3S1PR4S1PR5ADORA3 | |
| SCHEMBL22504242 | 0.84 | S1PR1 (0.42) | S1PR1S1PR3S1PR4S1PR5ADORA3 | |
| SCHEMBL20863953 | 0.84 | S1PR1 (0.42) | S1PR1S1PR3S1PR4S1PR5ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116730797-A | Preparation method of substituted benzene compound | 广东东阳光药业股份有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116730797-A | Preparation method of substituted benzene compound | 广东东阳光药业股份有限公司 | 2023-09-12 | — | — | CN | disclosed |
| US-20230212115-A1 | METHODS FOR THE PREPARATION OF SPHINGOSINE 1-PHOSPHATE RECEPTOR MODULATORS AND SOLID FORME THEREOF | CIPLA LIMITED (IN) | 2023-07-06 | — | — | US | disclosed |
| US-20230212115-A1 | METHODS FOR THE PREPARATION OF SPHINGOSINE 1-PHOSPHATE RECEPTOR MODULATORS AND SOLID FORME THEREOF | CIPLA LIMITED (IN) | 2023-07-06 | — | — | US | disclosed |
| US-20230212115-A1 | METHODS FOR THE PREPARATION OF SPHINGOSINE 1-PHOSPHATE RECEPTOR MODULATORS AND SOLID FORME THEREOF | CIPLA LIMITED (IN) | 2023-07-06 | — | — | US | disclosed |
| WO-2021240547-A2 | METHODS FOR THE PREPARATION OF SPHINGOSINE 1-PHOSPHATE RECEPTOR MODULATORS AND SOLID FORMS THEREOF | CIPLA LIMITED (IN) | 2021-12-02 | — | — | WO | disclosed |
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| EP-2017263-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2009-01-21 | — | — | EP | disclosed |
| EP-2017263-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2009-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212115-A1 | METHODS FOR THE PREPARATION OF SPHINGOSINE 1-PHOSPHATE RECEPTOR MODULATORS AND SOLID FORME THEREOF | S1PR1, S1PR2, S1PR3 | S1PR1 1/4885S1PR3 3/4885S1PR4 4/4885 |
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | S1PR3, S1PR2, S1PR1 | S1PR1 3/4885S1PR3 1/4885S1PR4 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.