⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056124 | 0.78 | — | — | |
| SCHEMBL11351432 | 0.76 | — | — | |
| SCHEMBL27982336 | 0.73 | — | — | |
| SCHEMBL11355628 | 0.72 | — | — | |
| SCHEMBL7055832 | 0.69 | — | — | |
| SCHEMBL17072496 | 0.67 | — | — | |
| SCHEMBL11346519 | 0.67 | — | — | |
| SCHEMBL1148435 | 0.65 | CA2 (0.34) | — | |
| SCHEMBL11359939 | 0.64 | CHRM1 (0.30) | — | |
| SCHEMBL164582 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2016070-A1 | INHIBITORS OF C-FMS KINASE | Janssen Pharmaceutica, N.V. (BE) | 2009-01-21 | — | — | EP | disclosed |
| WO-2007124319-A1 | INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-11-01 | — | — | WO | disclosed |