SCHEMBL3906707

SCHEMBL3906707

NCCCC(CCN)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.65
HTR2A P28223 2/20 0.65
ALDH1A1 P00352 1/20 0.45
TAAR1 Q96RJ0 3/20 0.44
GABBR2 O75899 2/20 0.42
GABBR1 Q9UBS5 2/20 0.42
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
TSHR P16473 1/20 0.41
SLC6A4 P31645 1/20 0.41
CYP2C19 P33261 1/20 0.41
SLC6A3 Q01959 1/20 0.41
MAOA P21397 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15776714 0.94 HRH1 (0.57) HRH1HTR2AALDH1A1TAAR1GABBR2
SCHEMBL11596175 0.87 HTR2A (0.65) HRH1HTR2ATAAR1GABBR2GABBR1
SCHEMBL6543317 0.86 HTR2A (0.59) HRH1HTR2AALDH1A1TAAR1GABBR2
SCHEMBL3389035 0.86 HTR2A (0.59) HRH1HTR2AALDH1A1TAAR1GABBR2
SCHEMBL9819733 0.84 HTR2A (0.57) HRH1HTR2ATAAR1CYP1A2CYP2D6
SCHEMBL11187960 0.84 MAOA (0.59) HRH1HTR2ATAAR1MAOA
SCHEMBL3428535 0.83 HRH1 (0.61) HRH1HTR2AALDH1A1TAAR1GABBR2
SCHEMBL11258097 0.83 HTR2A (0.49) HRH1HTR2AALDH1A1
SCHEMBL11312069 0.83 HTR2A (0.55) HRH1HTR2AALDH1A1TSHR
SCHEMBL9137323 0.82 HRH1 (0.62) HRH1HTR2AALDH1A1TAAR1GABBR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220089818-A1 BINDERS KNAUF INSULATION SPRL (BE) 2022-03-24 US disclosed
US-20220010067-A1 BINDERS KNAUF INSULATION SPRL (BE) 2022-01-13 US disclosed
US-20210332189-A1 BINDERS KNAUF INSULATION SPRL (BE) 2021-10-28 US disclosed
EP-3878881-A2 BINDERS Knauf Insulation SPRL (BE) 2021-09-15 EP disclosed
US-20210253795-A1 BINDERS KNAUF INSULATION SPRL (BE) 2021-08-19 US disclosed
US-20210171712-A1 BINDERS KNAUF INSULATION SPRL (BE) 2021-06-10 US disclosed
EP-2928935-B1 BINDERS KNAUF INSULATION SPRL (BE) 2021-03-31 EP disclosed
US-20210087339-A1 BINDERS KNAUF INSULATION SPRL (BE) 2021-03-25 US disclosed
US-20200362109-A1 BINDERS KNAUF INSULATION SPRL (BE) 2020-11-19 US disclosed
US-20200283578-A1 BINDERS KNAUF INSULATION SPRL (BE) 2020-09-10 US disclosed
US-20190202987-A1 BINDERS KNAUF INSULATION SPRL (BE) 2019-07-04 US disclosed
US-20190085128-A1 BINDERS KNAUF INSULATION SPRL (BE) 2019-03-21 US disclosed
US-20170130002-A1 BINDERS KNAUF INSULATION SPRL (BE) 2017-05-11 US disclosed
US-20150299391-A1 BINDERS Knauf Insulation ,LLC 2015-10-22 US disclosed
EP-2928935-A2 BINDERS Knauf Insulation SPRL (BE) 2015-10-14 EP disclosed
WO-2014086775-A2 BINDERS KNAUF INSULATION (BE) 2014-06-12 WO disclosed
WO-2009149143-A1 ADHESION OF POLYAMIDES TO EPOXY RESINS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-12-10 WO disclosed
EP-2019846-A1 HIGH MODULUS THERMOPLASTIC COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-02-04 EP disclosed
WO-2007139987-A1 HIGH MODULUS THERMOPLASTIC COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-12-06 WO disclosed
US-20070276081-A1 High modulus thermoplastic compositions E. I. DU PONT DE NEMOURS AND COMPANY 2007-11-29 US disclosed