Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.51 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 4/20 | 0.45 |
| ▸ | PLG | P00747 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.45 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.45 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HPN | P05981 | 1/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14132230 | 1.00 | F10 (0.51) | F10LNPEPSMN1; SMN2CYP2C19F2 | |
| Trifluoroacetic Acid SCHEMBL3907508 | 0.96 | F10 (0.50) | F10LNPEPSMN1; SMN2CYP2C19F2 | |
| Trifluoroacetic Acid SCHEMBL3900239 | 0.96 | F10 (0.50) | F10LNPEPSMN1; SMN2CYP2C19F2 | |
| SCHEMBL14132085 | 0.86 | ST14 (0.48) | F10LNPEPF2PLGHPN | |
| SCHEMBL14132231 | 0.86 | ST14 (0.53) | F10F2PLGHPNST14 | |
| SCHEMBL14132293 | 0.83 | F10 (0.57) | F10F2PLGHPNST14 | |
| Trifluoroacetic Acid SCHEMBL3905613 | 0.83 | ST14 (0.50) | F10F2PLGHPNST14 | |
| Trifluoroacetic Acid SCHEMBL3900465 | 0.83 | F10 (0.47) | F10LNPEPF2PLGHPN | |
| SCHEMBL14132066 | 0.83 | ITGB3 (0.46) | F10LNPEPF2PLGHPN | |
| Trifluoroacetic Acid SCHEMBL3898369 | 0.80 | F10 (0.44) | F10LNPEPF2PLGHPN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |