SCHEMBL3907385

SCHEMBL3907385

O=C(O)C1(C(=O)O)CCC1.[Ag]

nearest known ligand 0.93

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.38
CYP2C19 P33261 2/20 0.35
CYP2D6 P10635 1/20 0.33
AKR1C1 Q04828 1/20 0.32
TSHR P16473 1/20 0.30
NFKB1 P19838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8533386 1.00 FFAR3 (0.38) FFAR3CYP2C19CYP2D6AKR1C1TSHR
SCHEMBL8907359 0.97 FFAR3 (0.40) FFAR3CYP2C19CYP2D6AKR1C1TSHR
SCHEMBL127199 0.97 FFAR3 (0.40) FFAR3CYP2C19CYP2D6AKR1C1TSHR
Hydrochloric Acid SCHEMBL1189681 0.93 FFAR3 (0.38) FFAR3CYP2C19CYP2D6AKR1C1TSHR
Bromide SCHEMBL16086037 0.93 FFAR3 (0.38) FFAR3CYP2C19CYP2D6AKR1C1TSHR
SCHEMBL9619104 0.93 FFAR3 (0.38) FFAR3CYP2C19CYP2D6AKR1C1TSHR
Hydrochloric Acid SCHEMBL809129 0.93 FFAR3 (0.38) FFAR3CYP2C19CYP2D6AKR1C1TSHR
SCHEMBL7766381 0.93 FFAR3 (0.38) FFAR3CYP2C19CYP2D6AKR1C1TSHR
SCHEMBL5367504 0.93 FFAR3 (0.38) FFAR3CYP2C19CYP2D6AKR1C1TSHR
SCHEMBL21295011 0.93 CYP2C19 (0.40) FFAR3CYP2C19CYP2D6AKR1C1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115165771-A Control method for silver content in platinum anticancer drug synthesized by silver salt method 昆明贵研药业有限公司 2022-10-11 CN claimed
CN-108521780-A The method that one kettle way prepares bis-dicarboxylic diamino platinum (II) derivative 昆明贵研药业有限公司 2018-09-11 CN claimed
JP-2028134-A None JP disclosed
JP-2028135-A None JP disclosed
JP-62298596-A None JP disclosed
CN-108521780-B Method for preparing bis-dicarboxylic acid diammine platinum (II) derivative by one-pot method 昆明贵研药业有限公司 2024-08-02 CN disclosed
CN-106543233-B Chiral binuclear platinum complex containing unsaturated bond and preparation method and application thereof 昆明理工大学 2021-04-09 CN disclosed
CN-106565859-B Cyclodextrin-bonded object of a kind of chirality platinum-and its preparation method and application 昆明理工大学 2019-09-27 CN disclosed
WO-2019161526-A1 ONE-POT METHOD FOR PREPARING TWIN DICARBOXYLIC ACID DIAMINE COMPLEX PLATINUM (II) DERIVATIVES 昆明贵研药业有限公司 2019-08-29 WO disclosed
CN-108521780-A The method that one kettle way prepares bis-dicarboxylic diamino platinum (II) derivative 昆明贵研药业有限公司 2018-09-11 CN disclosed
CN-106543233-A The chiral binuclear platinum complex of one class containing unsaturated bond and its preparation method and application 昆明理工大学 2017-03-29 CN disclosed
EP-1282631-B1 METHODS OF SYNTHESIS OF RADIOLABELLED PLATINUM CHEMOTHERAPEUTIC AGENTS AUSTRALIAN NUCLEAR SCIENCE TEC (AU) 2008-09-03 EP disclosed
WO-2007128158-A1 TRANSITION METAL COMPLEXES FOR INHIBITING RESISTANCE IN THE TREATMENT OF CANCER AND METASTASIS ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2007-11-15 WO disclosed
US-7108845-B2 Methods of synthesis and use of radiolabelled platinum chemotherapeutic agents AUSTRALIAN NUCLEAR SCIENCE & TECHNOLOGY ORGANISATION (AU) 2006-09-19 US disclosed
US-20030103896-A1 Methods of synthesis and use of radiolabelled platinum chemotherapeutic agents AUSTRALIAN NUCLEAR SCIENCE & TECHNOLOGY ORGANISATION (AU) 2003-06-05 US disclosed
EP-1282631-A1 METHODS OF SYNTHESIS AND USE OF RADIOLABELLED PLATINUM CHEMOTHERAPEUTIC AGENTS AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION (AU) 2003-02-12 EP disclosed
WO-2001070755-A1 METHODS OF SYNTHESIS AND USE OF RADIOLABELLED PLATINUM CHEMOTHERAPEUTIC AGENTS AUSTRALIAN NUCLEAR SCIENCE & TECHNOLOGY ORGANISATION (AU) 2001-09-27 WO disclosed
JP-H0228134-A PREPARATION OF CARBOXYLATO(DIAMINE) PLATINUM CHUGAI PHARMACEUT CO LTD 1990-01-30 JP disclosed
JP-H0228135-A PREPARATION OF PLATINUM COMPLEX CHUGAI PHARMACEUT CO LTD 1990-01-30 JP disclosed
JP-S62298596-A PRODUCTION OF PLATINUM COMPLEX CHUGAI PHARMACEUT CO LTD 1987-12-25 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030103896-A1 Methods of synthesis and use of radiolabelled platinum chemotherapeutic agents REV1, IDH1, PAICS FFAR3 4716/4885CYP2C19 1462/4885CYP2D6 487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.