Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 3/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3905074 | 0.90 | CASR (0.53) | CASROPRM1OPRL1ALDH1A1MEN1 | |
| SCHEMBL3910532 | 0.90 | CASR (0.44) | CASROPRM1OPRL1CNR1MEN1 | |
| SCHEMBL3908102 | 0.86 | CASR (0.47) | CASROPRM1OPRL1ALDH1A1TRPM8 | |
| SCHEMBL3911797 | 0.85 | CASR (0.46) | CASROPRM1OPRL1MEN1KMT2A | |
| SCHEMBL3916716 | 0.78 | CASR (0.53) | CASROPRM1OPRL1CNR1ALDH1A1 | |
| SCHEMBL3908089 | 0.78 | CASR (0.53) | CASROPRL1CNR1SLC6A3 | |
| SCHEMBL3282680 | 0.77 | CNR1 (0.47) | CASRCNR1ALDH1A1MEN1KMT2A | |
| SCHEMBL3905381 | 0.77 | CASR (0.45) | CASROPRL1ALDH1A1SLC6A3 | |
| SCHEMBL3906098 | 0.76 | OPRL1 (0.56) | CASROPRM1OPRL1 | |
| SCHEMBL3914023 | 0.75 | OPRM1 (0.41) | CASROPRM1OPRL1CNR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | claimed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | claimed |
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |