⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68569 | 0.93 | — | — | |
| SCHEMBL5075588 | 0.90 | CA1 (0.38) | — | |
| SCHEMBL15856951 | 0.90 | CA1 (0.38) | — | |
| SCHEMBL159029 | 0.90 | CA1 (0.38) | — | |
| SCHEMBL14463171 | 0.90 | CA1 (0.38) | — | |
| SCHEMBL14641415 | 0.90 | CA1 (0.38) | — | |
| SCHEMBL18811684 | 0.90 | CA1 (0.38) | — | |
| SCHEMBL5075567 | 0.90 | CA1 (0.38) | — | |
| SCHEMBL22022206 | 0.90 | CA1 (0.38) | — | |
| SCHEMBL14548867 | 0.90 | CA1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 366 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122080012-A | Thienopyrimidine derivative, preparation method, application and pharmaceutical composition thereof | — | 2026-05-26 | — | — | CN | disclosed |
| US-20260109711-A1 | MACROCYCLIC SULFONAMIDE MODULATORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2026-04-23 | — | — | US | disclosed |
| EP-4263518-B1 | NEW QUINAZOLINONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2026-04-01 | — | — | EP | disclosed |
| US-20260078091-A1 | Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer | AMGEN INC (US) | 2026-03-19 | — | — | US | disclosed |
| US-12570615-B2 | Quinazolinone derivatives | HOFFMANN-LA ROCHE INC. | 2026-03-10 | — | — | US | disclosed |
| EP-4703353-A1 | PESTICIDALLY-ACTIVE 2,2-DIHALOCYCLOPROPYL COMPOUNDS | Syngenta Crop Protection AG (CH) | 2026-03-04 | — | — | EP | disclosed |
| US-20250270180-A1 | MEK INHIBITORS AND THERAPEUTIC USES THEREOF | IMMUNEERING CORPORATION | 2025-08-28 | — | — | US | disclosed |
| US-12351566-B2 | MEK inhibitors and therapeutic uses thereof | IMMUNEERING CORPORATION (US) | 2025-07-08 | — | — | US | disclosed |
| EP-4563579-A1 | MACROCYCLIC EGFR INHIBITOR, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2025-06-04 | — | — | EP | disclosed |
| WO-2025096858-A1 | COMPOUNDS FOR THE DEGRADATION OF MUTANT BRAF | C4 THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| US-7220881-B2 | Process for production of acid anhydride | TOKUYAMA CORPORATION (JP) | 2007-05-22 | — | — | US | disclosed |
| WO-2007014011-A2 | N-(ARYLAMINO)-SULFONAMIDE INHIBITORS OF MEK | ARDEA BIOSCIENCES, INC. (US) | 2007-02-01 | — | — | WO | disclosed |
| EP-1230224-B1 | SUBSTITUTED 5-BENZYL-2,4-DIAMINOPYRIMIDINES | BASILEA PHARMACEUTICA AG (CH) | 2004-12-29 | — | — | EP | disclosed |
| US-20040242929-A1 | Process for production of acid anhydride | TOKUYAMA CORPORATION (JP) | 2004-12-02 | — | — | US | disclosed |
| US-6821980-B1 | Substituted 5-benzyl-2,4-diaminopyrimidines | BASILEA PHARMACEUTICA AG (CH) | 2004-11-23 | — | — | US | disclosed |
| EP-1413572-A1 | PROCESS FOR PRODUCING ACID ANHYDRIDE | Tokuyama Corporation (JP) | 2004-04-28 | — | — | EP | disclosed |
| US-6716843-B2 | INHIBITOR OF DIPEPTIDYL-PEPTIDASE IV | LES LABORATOIRES SERVIER (FR) | 2004-04-06 | — | — | US | disclosed |
| US-20030087950-A1 | New alpha-amino acid sulphonyl compounds | LES LABORATOIRES SERVIER (FR) | 2003-05-08 | — | — | US | disclosed |
| EP-1230224-A1 | SUBSTITUTED 5-BENZYL-2,4-DIAMINOPYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001032633-A1 | SUBSTITUTED 5-BENZYL-2,4-DIAMINOPYRIMIDINES | BASILEA PHARMACEUTICA AG (CH) | 2001-05-10 | — | — | WO | disclosed |