Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 2/20 | 0.31 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14548867 | 1.00 | CA1 (0.38) | CA1CA12CA7CA14CA2 | |
| SCHEMBL22022206 | 1.00 | CA1 (0.38) | CA1CA12CA7CA14CA2 | |
| SCHEMBL159029 | 1.00 | CA1 (0.38) | CA1CA12CA7CA14CA2 | |
| SCHEMBL14641415 | 1.00 | CA1 (0.38) | CA1CA12CA7CA14CA2 | |
| SCHEMBL14463171 | 1.00 | CA1 (0.38) | CA1CA12CA7CA14CA2 | |
| SCHEMBL15856951 | 1.00 | CA1 (0.38) | CA1CA12CA7CA14CA2 | |
| SCHEMBL18811684 | 1.00 | CA1 (0.38) | CA1CA12CA7CA14CA2 | |
| SCHEMBL5075588 | 1.00 | CA1 (0.38) | CA1CA12CA7CA14CA2 | |
| Hydrogen Sulfide SCHEMBL27532786 | 0.97 | CA1 (0.36) | CA1CA12CA7CA14CA2 | |
| SCHEMBL68569 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246117-A1 | PROCESSES FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS (SAN DIEGO) LLC | 2021-08-12 | — | — | US | disclosed |
| WO-2019113476-A2 | PROCESSES FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2019-06-13 | — | — | WO | disclosed |
| EP-1413572-B1 | PROCESS FOR PRODUCING ACID ANHYDRIDE | TOKUYAMA CORP (JP) | 2008-10-08 | — | — | EP | disclosed |
| US-7220881-B2 | Process for production of acid anhydride | TOKUYAMA CORPORATION (JP) | 2007-05-22 | — | — | US | disclosed |
| US-20070021607-A1 | Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them | ABBOTT GMBH & CO. KG. | 2007-01-25 | — | — | US | disclosed |
| CN-1220676-C | Method for producing acid anhydride | TOKUYAMA CORP (JP) | 2005-09-28 | — | — | CN | disclosed |
| US-20040242929-A1 | Process for production of acid anhydride | TOKUYAMA CORPORATION (JP) | 2004-12-02 | — | — | US | disclosed |
| CN-1537097-A | Method for producing acid anhydride | ��ʽ�����ɽ | 2004-10-13 | — | — | CN | disclosed |
| EP-1413572-A1 | PROCESS FOR PRODUCING ACID ANHYDRIDE | Tokuyama Corporation (JP) | 2004-04-28 | — | — | EP | disclosed |
| EP-0788796-A1 | URICOSURIC AGENT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210246117-A1 | PROCESSES FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SCNN1B, SCNN1G | CA1 4860/4885CA12 4658/4885CA7 4575/4885 |
| US-20070021607-A1 | Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them | OXTR, AVPR2, AVPR1A | CA1 3128/4885CA12 3472/4885CA7 4285/4885 |
| US-20040242929-A1 | Process for production of acid anhydride | CA4, CA9, CA6 | CA1 8/4885CA12 6/4885CA7 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.