SCHEMBL3907985

SCHEMBL3907985

O=CC=Cc1ccc(OCc2ccccc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCNB2 O95067 2/20 0.70
CDK1 P06493 2/20 0.70
CDK4 P11802 2/20 0.70
CCNB1 P14635 2/20 0.70
CCND1 P24385 2/20 0.70
CCNB3 Q8WWL7 2/20 0.70
GSK3B P49841 3/20 0.63
BACE1 P56817 3/20 0.63
LCK P06239 1/20 0.60
SLC5A1 P13866 1/20 0.57
SLC5A2 P31639 1/20 0.57
PPARG P37231 1/20 0.56
ABCG2 Q9UNQ0 1/20 0.56
LMNA P02545 2/20 0.55
TRPA1 O75762 1/20 0.55
ALDH1A1 P00352 1/20 0.55
ALOX5 P09917 1/20 0.55
MAPK1 P28482 1/20 0.55
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7806237 1.00 CCNB2 (0.70) CCNB2CDK1CDK4CCNB1CCND1
SCHEMBL13802183 0.88 CCNB2 (0.76) CCNB2CDK1CDK4CCNB1CCND1
SCHEMBL13284951 0.86 CCNB2 (0.65) CCNB2CDK1CDK4CCNB1CCND1
SCHEMBL20024692 0.86 LCK (0.77) GSK3BBACE1LCKPPARGABCG2
SCHEMBL14786203 0.86 LCK (0.77) GSK3BBACE1LCKPPARGABCG2
SCHEMBL8913590 0.84 LCK (0.81) GSK3BBACE1LCKPPARGABCG2
SCHEMBL8913578 0.84 LCK (0.81) GSK3BBACE1LCKPPARGABCG2
SCHEMBL28757264 0.83 LCK (0.60) CCNB2CDK1CDK4CCNB1CCND1
SCHEMBL5889707 0.83 CCNB2 (0.73) CCNB2CDK1CDK4CCNB1CCND1
SCHEMBL5889708 0.83 CCNB2 (0.73) CCNB2CDK1CDK4CCNB1CCND1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116462608-B Allyl arene derivative and preparation method and application thereof 河北科技大学 2025-01-28 CN disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
CN-116462608-A Allyl arene derivative and preparation method and application thereof 河北科技大学 2023-07-21 CN disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
CN-108840788-B Preparation method of resveratrol 扬州大学 2021-06-08 CN disclosed
EP-2015645-A2 EXTRACTS AND METHODS COMPRISING CINNAMON SPECIES Herbalscience Singapore Pte. Ltd. (US) 2009-01-21 EP disclosed
WO-2007109804-A2 EXTRACTS AND METHODS COMPRISING CINNAMON SPECIES HERBALSCIENCE SINGAPORE PTE. LTD. (US) 2007-09-27 WO disclosed
US-6548096-B1 Aspartyl dipeptide ester derivatives and sweeteners AJINOMOTO CO., INC. (JP) 2003-04-15 US disclosed
EP-1070726-A1 ASPARTYL DIPEPTIDE ESTER DERIVATIVES AND SWEETENERS Ajinomoto Co., Inc. (JP) 2001-01-24 EP disclosed
WO-1997000249-A1 HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-01-03 WO disclosed
EP-0189142-A2 Arylalkoxyphenyl-allylic alcohols as agents for the treatment of hypersensitive ailments USV PHARMACEUTICAL CORPORATION (US) 1986-07-30 EP disclosed
US-4262013-A ANTILIPEMIC AGENTS SANKYO COMPANY LIMITED (JP) 1981-04-14 US disclosed
US-4198425-A ANTILIPEMIC AGENTS SANKYO COMPANY LIMITED (JP) 1980-04-15 US disclosed
US-4014899-A ANTIASTHMATIC AND ANTIALLERGIC AGENTS CIBA-GEIGY CORPORATION (US) 1977-03-29 US disclosed
US-3973030-A Antiasthmatic 5,6-benzoisoindoline compositions CIBA-GEIGY CORPORATION (US) 1976-08-03 US disclosed