Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 3/20 | 0.76 |
| ▸ | CDK1 | P06493 | 3/20 | 0.76 |
| ▸ | CDK4 | P11802 | 3/20 | 0.76 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.76 |
| ▸ | CCND1 | P24385 | 3/20 | 0.76 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.76 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.61 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.49 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7806237 | 0.88 | CCNB2 (0.70) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL3907985 | 0.88 | CCNB2 (0.70) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL7264492 | 0.87 | CCNB2 (1.00) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL7264489 | 0.87 | CCNB2 (1.00) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL3904670 | 0.86 | MAOA (0.71) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL1481374 | 0.81 | KDM4E (0.77) | ALOX5LCKMAOBKDM4EALDH1A1 | |
| SCHEMBL1481376 | 0.81 | KDM4E (0.77) | ALOX5LCKMAOBKDM4EALDH1A1 | |
| SCHEMBL5889707 | 0.81 | CCNB2 (0.73) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL5889708 | 0.81 | CCNB2 (0.73) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL7086040 | 0.81 | CCNB2 (0.65) | CCNB2CDK1CDK4CCNB1CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553867-B2 | Furan or thiophene derivative and medicinal use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-30 | — | — | US | disclosed |