Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 3/20 | 0.53 |
| ▸ | P4HB | P07237 | 10/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3908239 | 1.00 | FBP1 (0.53) | FBP1P4HBMAOAMAOBGRIN2D | |
| SCHEMBL2774364 | 0.82 | FBP1 (0.65) | FBP1P4HBMAOAMAOBGRIN2D | |
| SCHEMBL1687910 | 0.82 | FBP1 (0.65) | FBP1P4HBMAOAMAOBGRIN2D | |
| SCHEMBL6166447 | 0.82 | FBP1 (0.53) | FBP1P4HBMAOAMAOBGRIN2D | |
| SCHEMBL5864935 | 0.82 | FBP1 (0.53) | FBP1P4HBMAOAMAOBGRIN2D | |
| SCHEMBL5783464 | 0.82 | FBP1 (0.53) | FBP1P4HBMAOAMAOBGRIN2D | |
| SCHEMBL924068 | 0.82 | FBP1 (0.53) | FBP1P4HBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL924069 | 0.82 | FBP1 (0.53) | FBP1P4HBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL6165260 | 0.82 | FBP1 (0.53) | FBP1P4HBMAOAMAOBGRIN2D | |
| SCHEMBL6165255 | 0.82 | FBP1 (0.53) | FBP1P4HBMAOAMAOBGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |
| CN-1243505-A | Benzamidine derivatives | AJINOMOTO KK (JP) | 2000-02-02 | — | — | CN | disclosed |
| EP-0347766-B1 | 4,5,7,8-Tetrahydro-6H-thiazolo[5,4-d]azepines, their preparation and their use as medicaments | THOMAE GMBH DR K (DE) | 1994-05-25 | — | — | EP | disclosed |
| US-5068325-A | Dopaminergic systems as hypotensives, sedatives, antitussives and/or antiphlogistics | KARL THOMAE GMBH (DE) | 1991-11-26 | — | — | US | disclosed |