Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.73 |
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.72 |
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | PNMT | P11086 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6862516 | 0.84 | DPP4 (1.00) | DPP4TAAR1MAOBPNMTCYP1A2 | |
| SCHEMBL266281 | 0.84 | TAAR1 (1.00) | DPP4TAAR1MAOBPNMTCYP1A2 | |
| SCHEMBL29351771 | 0.84 | TAAR1 (1.00) | DPP4TAAR1MAOBPNMTCYP1A2 | |
| Ammonia Solution, Strong SCHEMBL7423333 | 0.82 | TAAR1 (0.95) | DPP4TAAR1MAOBPNMTCYP1A2 | |
| Iodide SCHEMBL30914653 | 0.82 | TAAR1 (0.95) | DPP4TAAR1MAOBPNMTCYP1A2 | |
| Hydrochloric Acid SCHEMBL1847347 | 0.82 | TAAR1 (0.95) | DPP4TAAR1MAOBPNMTCYP1A2 | |
| SCHEMBL21848195 | 0.82 | TAAR1 (0.95) | DPP4TAAR1MAOBPNMTCYP1A2 | |
| Hydrochloric Acid SCHEMBL31521506 | 0.82 | TAAR1 (0.95) | DPP4TAAR1MAOBPNMTCYP1A2 | |
| SCHEMBL3903028 | 0.78 | TAAR1 (0.68) | DPP4TAAR1MAOBHTR2AADRA2C | |
| SCHEMBL29512902 | 0.77 | DPP4 (0.57) | DPP4TAAR1MAOBHTR2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |