Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318920 | 0.81 | CPA1 (0.62) | ERCC5FEN1MAPTALDH1A1TSHR | |
| SCHEMBL6046233 | 0.78 | ERCC5 (0.53) | ERCC5FEN1MAPTALDH1A1POLB | |
| SCHEMBL27564320 | 0.76 | ERCC5 (0.54) | ERCC5FEN1MAPTALDH1A1POLB | |
| SCHEMBL7312766 | 0.73 | ALDH1A1 (0.50) | ERCC5FEN1ALDH1A1POLBHPGD | |
| SCHEMBL6932749 | 0.73 | — | — | |
| SCHEMBL17503961 | 0.72 | ERCC5 (0.44) | ERCC5FEN1MAPTALDH1A1POLB | |
| SCHEMBL2589028 | 0.72 | CYP1A2 (0.70) | CYP1A2CPA1CPB1CPA3CPB2 | |
| SCHEMBL14073806 | 0.72 | ALDH1A1 (0.56) | ERCC5FEN1MAPTALDH1A1POLB | |
| SCHEMBL7902879 | 0.71 | KMT2A (0.56) | ERCC5FEN1MAPTALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL4971503 | 0.71 | ALDH1A1 (0.56) | ERCC5FEN1MAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601370-B2 | Method for controlling body weight in estrogen-insufficient women | ABBOTT LABORATORIES (US) | 2009-10-13 | — | — | US | disclosed |
| US-7435431-B2 | Method for controlling body weight in estrogen-insufficient women | ABBOTT LABORATORIES (US) | 2008-10-14 | — | — | US | disclosed |
| US-20080242592-A1 | METHOD FOR CONTROLLING BODY WEIGHT IN ESTROGEN-INSUFFICIENT WOMEN | ABBOTT LABORATORIES (US) | 2008-10-02 | — | — | US | disclosed |
| EP-1773364-B1 | NUTRITIONAL COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING OSTEOPOROSIS | ABBOTT LAB (US) | 2008-10-01 | — | — | EP | disclosed |
| WO-2008076579-A2 | METHOD OF CONTROLLING BODY WEIGHT IN ESTROGEN-INSUFFICIENT WOMEN | ABBOT LABORATORIES (US) | 2008-06-26 | — | — | WO | disclosed |
| US-20070098821-A1 | Method for controlling body weight in estrogen-insufficient women | ABBOTT LABORATORIES | 2007-05-03 | — | — | US | disclosed |
| US-20060040001-A1 | Nutritional compositions and methods for treating or preventing osteoporosis | ABBOTT LABORATORIES | 2006-02-23 | — | — | US | disclosed |