⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL64072 | 0.74 | CYP3A4 (0.33) | — | |
| SCHEMBL4262425 | 0.73 | — | — | |
| SCHEMBL1979559 | 0.73 | — | — | |
| SCHEMBL4553769 | 0.73 | — | — | |
| SCHEMBL3955049 | 0.73 | — | — | |
| SCHEMBL28819045 | 0.73 | CYP3A4 (0.32) | — | |
| SCHEMBL6131635 | 0.73 | — | — | |
| SCHEMBL30106704 | 0.73 | — | — | |
| Dimethylamine SCHEMBL29101974 | 0.72 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL16752481 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107722010-A | A kind of hypoxemia activation chlorethylnitrosourea containing nitroimidazole group and its preparation method and application | 北京工业大学 | 2018-02-23 | — | — | CN | claimed |
| EP-2027079-A2 | GAS GENERATION WITH COPPER COMPLEXED IMIDAZOLE AND DERIVATIVES | Autoliv ASP, INC. (US) | 2009-02-25 | — | — | EP | claimed |
| US-7470337-B2 | Gas generation with copper complexed imidazole and derivatives | AUTOLIV ASP, INC. (US) | 2008-12-30 | — | — | US | claimed |
| WO-2008051274-A2 | GAS GENERATION WITH COPPER COMPLEXED IMIDAZOLE AND DERIVATIVES | AUTOLIV ASP, INC. (US) | 2008-05-02 | — | — | WO | claimed |
| US-20070240797-A1 | Gas generation with copper complexed imidazole and derivatives | AUTOLIV ASP, INC. | 2007-10-18 | — | — | US | claimed |
| CN-116803989-A | Preparation process of 1-N-methyl-2-nitro-5-hydroxymethyl imidazole | 深圳艾欣达伟医药科技有限公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-107722010-A | A kind of hypoxemia activation chlorethylnitrosourea containing nitroimidazole group and its preparation method and application | 北京工业大学 | 2018-02-23 | — | — | CN | disclosed |
| US-20160296538-A1 | PREDICTIVE AND RESPONSE BIOMARKER FOR TH-302 ANTI-CANCER THERAPY | THRESHOLD PHARMACEUTICALS, INC. (US) | 2016-10-13 | — | — | US | disclosed |
| CN-101616695-B | The alkalescence 2-nitroimidazole of histanoxia is detected for Noninvasive | NATURAL PHARMACIA INTERNATIONAL, INC. (US) | 2016-03-16 | — | — | CN | disclosed |
| EP-2983591-A1 | PREDICTIVE AND RESPONSE BIOMARKER FOR TH-302 ANTI-CANCER THERAPY | Threshold Pharmaceuticals, Inc. (US) | 2016-02-17 | — | — | EP | disclosed |
| WO-2014169035-A1 | PREDICTIVE AND RESPONSE BIOMARKER FOR TH-302 ANTI-CANCER THERAPY | THRESHOLD PHARMACEUTICALS, INC. (US) | 2014-10-16 | — | — | WO | disclosed |
| WO-2014030142-A2 | NITROIMIDAZOLE COMPOUNDS AND THEIR USE IN CANCER THERAPY | AUCKLAND UNISERVICES LIMITED (NZ) | 2014-02-27 | — | — | WO | disclosed |
| CN-101616695-A | Be used for the Noninvasive detection and organize anoxybiotic alkalescence 2-nitroimidazole | NATURAL PHARMACIA INTERNATIONA | 2009-12-30 | — | — | CN | disclosed |
| EP-2027079-A2 | GAS GENERATION WITH COPPER COMPLEXED IMIDAZOLE AND DERIVATIVES | Autoliv ASP, INC. (US) | 2009-02-25 | — | — | EP | disclosed |
| US-7470337-B2 | Gas generation with copper complexed imidazole and derivatives | AUTOLIV ASP, INC. (US) | 2008-12-30 | — | — | US | disclosed |
| WO-2008051274-A2 | GAS GENERATION WITH COPPER COMPLEXED IMIDAZOLE AND DERIVATIVES | AUTOLIV ASP, INC. (US) | 2008-05-02 | — | — | WO | disclosed |
| US-20070240797-A1 | Gas generation with copper complexed imidazole and derivatives | AUTOLIV ASP, INC. | 2007-10-18 | — | — | US | disclosed |
| US-5668127-A | MYCOBACTERIUM TUBERCULOSIS, CLOSTRIDIUM | PATHOGENESIS CORPORATION (US) | 1997-09-16 | — | — | US | disclosed |