SCHEMBL4262425

SCHEMBL4262425

Nc1c[nH]c([N+](=O)[O-])n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL64072 0.74 CYP3A4 (0.33)
SCHEMBL28013221 0.73 CYP3A4 (0.32)
SCHEMBL27960253 0.73 CYP3A4 (0.32)
SCHEMBL28013804 0.73 CYP3A4 (0.32)
SCHEMBL4553769 0.73
SCHEMBL3908846 0.73
SCHEMBL3955049 0.73
SCHEMBL28819045 0.73 CYP3A4 (0.32)
SCHEMBL6131635 0.73
SCHEMBL30106704 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117919453-A Preparation method of MRI/CT multi-mode probe 中国科学院宁波材料技术与工程研究所 2024-04-26 CN claimed
CN-117919453-A Preparation method of MRI/CT multi-mode probe 中国科学院宁波材料技术与工程研究所 2024-04-26 CN disclosed
CN-117919453-A Preparation method of MRI/CT multi-mode probe 中国科学院宁波材料技术与工程研究所 2024-04-26 CN disclosed
WO-2011087995-A2 ORGANIC COMPOUNDS BARRY CLIFTON (US) 2011-07-21 WO disclosed
US-20090124593-A1 Pharmaceutical Compositions Primarily for the Treatment and Prevention of Genitourinary Infections and their ExtraGenital Complications MARTON MILANKOVITS 2009-05-14 US disclosed
US-20090074839-A1 Pharmaceutical Compositions Primarily for the Treatment and Prevention of Genitourinary Infections and their Extragenital Complications MILANKOVITS MARTON 2009-03-19 US disclosed
US-20050208152-A1 Pharmaceutical compositions primarily for the treatment and prevention of genitourinary infections and their extragenital complications MILANKOVITS MARTON 2005-09-22 US disclosed
US-4282232-A Nitroimidazole radiosensitizers for hypoxic tumor cells and compositions thereof RESEARCH CORPORATION (US) 1981-08-04 US disclosed