Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 6/20 | 0.49 |
| ▸ | TMPRSS6 | Q8IU80 | 4/20 | 0.49 |
| ▸ | PLG | P00747 | 2/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | C1S | P09871 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3901330 | 1.00 | F10 (0.52) | F10CTSLCTSBCTSSCTSK | |
| SCHEMBL14132266 | 0.97 | F10 (0.55) | F10CTSLCTSBCTSSCTSK | |
| SCHEMBL14132050 | 0.97 | F10 (0.55) | F10CTSLCTSBCTSSCTSK | |
| Trifluoroacetic Acid SCHEMBL3898325 | 0.92 | F10 (0.49) | F10CTSLCTSSCTSKITGB3 | |
| Trifluoroacetic Acid SCHEMBL5096424 | 0.91 | SIRT2 (0.53) | F10CTSLCTSSITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL3900546 | 0.91 | F10 (0.45) | F10CTSLCTSBCTSSCTSK | |
| Trifluoroacetic Acid SCHEMBL5092493 | 0.91 | F10 (0.52) | F10CTSLCTSSCTSKITGB3 | |
| Trifluoroacetic Acid SCHEMBL3897942 | 0.91 | F10 (0.52) | F10CTSLCTSSCTSKITGB3 | |
| SCHEMBL14132310 | 0.88 | F10 (0.52) | F10CTSLCTSSCTSKF2 | |
| SCHEMBL3898330 | 0.87 | F10 (0.47) | F10CTSLCTSSCTSKF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |