Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.53 |
| ▸ | CPB1 | P15086 | 1/20 | 0.50 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3908350 | 0.97 | SIRT2 (0.55) | SIRT2SIRT1SIRT3CPB1CPB2 | |
| Trifluoroacetic Acid SCHEMBL3898325 | 0.91 | F10 (0.49) | SIRT2SIRT1SIRT3ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL3901330 | 0.91 | F10 (0.52) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL3909089 | 0.91 | F10 (0.52) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL14132266 | 0.88 | F10 (0.55) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL14132050 | 0.88 | F10 (0.55) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL14132310 | 0.88 | F10 (0.52) | SIRT2SIRT1SIRT3TPSAB1PRSS1 | |
| Trifluoroacetic Acid SCHEMBL3897942 | 0.87 | F10 (0.52) | SIRT2ITGB3ITGA2BTPSAB1PRSS1 | |
| Trifluoroacetic Acid SCHEMBL5092493 | 0.87 | F10 (0.52) | SIRT2ITGB3ITGA2BTPSAB1PRSS1 | |
| SCHEMBL3898330 | 0.87 | F10 (0.47) | SIRT2SIRT1SIRT3TPSAB1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |