Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL3909560

O=C=NC1CCCC(N=C=O)C1N=C=O.S

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7782863 0.97 ALDH1A1 (0.44) ALDH1A1
SCHEMBL15011581 0.87 ALDH1A1 (0.42) ALDH1A1
SCHEMBL26610 0.84 ALDH1A1 (0.50) ALDH1A1
SCHEMBL48400 0.82 ALDH1A1 (0.37) ALDH1A1
SCHEMBL29007560 0.81 ALDH1A1 (0.42) ALDH1A1
SCHEMBL1890241 0.81 ALDH1A1 (0.35) ALDH1A1
SCHEMBL5460574 0.78 ALDH1A1 (0.57) ALDH1A1
SCHEMBL26012 0.78 ALDH1A1 (0.57) ALDH1A1
SCHEMBL9323923 0.78 ALDH1A1 (0.57) ALDH1A1
SCHEMBL3661081 0.78 ALDH1A1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10144760-B2 Ligand functional substrates 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-12-04 US disclosed
US-20160152662-A1 LIGAND FUNCTIONAL SUBSTRATES SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2016-06-02 US disclosed
US-9272246-B2 Ligand functional substrates 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-03-01 US disclosed
US-9217050-B2 Crosslinkable composition comprising photobase generators 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-12-22 US disclosed
US-20150232596-A1 CROSSLINKABLE COMPOSITION COMPRISING PHOTOBASE GENERATORS 3M INNOVATIVE PROPERTIES COMPANY 2015-08-20 US disclosed
US-20120252091-A1 LIGAND FUNCTIONAL SUBSTRATES 3M INNOVATIVE PROPERTIES COMPANY 2012-10-04 US disclosed
US-7585919-B2 Polymer derived from monomers with long-chain aliphatic, poly(oxyalkylene) and substrate-reactive groups 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-09-08 US disclosed
CN-101516926-A Curable compositions and biofilm-resistant coatings therefrom 3M INNOVATIVE PROPERTIES CO (US) 2009-08-26 CN disclosed
US-7459167-B1 Biocidal polyurethane compositions and methods of use 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-12-02 US disclosed
EP-1935911-A1 Biocidal Polyurethane Compositions and Method of Use 3M Innovative Properties Company (US) 2008-06-25 EP disclosed
US-20080075960-A1 CURABLE COMPOSITIONS AND BIOFILM-RESISTANT COATINGS THEREFROM 3M INNOVATIVE PROPERTIES COMPANY 2008-03-27 US disclosed
EP-1311572-A2 BIOCIDAL POLYURETHANE COMPOSITIONS AND METHOD OF USE 3M Innovative Properties Company (US) 2003-05-21 EP disclosed
WO-2002010244-A2 BIOCIDAL POLYURETHANE COMPOSITIONS AND METHOD OF USE 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-02-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10144760-B2 Ligand functional substrates PCNA, POLM, POLL ALDH1A1 4565/4885
US-20120252091-A1 LIGAND FUNCTIONAL SUBSTRATES PCNA, POLM, POLL ALDH1A1 4565/4885
US-20160152662-A1 LIGAND FUNCTIONAL SUBSTRATES PCNA, POLM, POLL ALDH1A1 4565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.