Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 5/20 | 0.52 |
| ▸ | GSK3B | P49841 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.46 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264757 | 0.78 | GSK3A (0.54) | GSK3AGSK3BGAANTRK1IGF1R | |
| SCHEMBL5326615 | 0.76 | GSK3A (0.55) | GSK3AGSK3BGAANTRK1IGF1R | |
| SCHEMBL23895082 | 0.74 | GSK3A (0.50) | GSK3AGSK3BGAANTRK1IGF1R | |
| SCHEMBL5198556 | 0.74 | NTRK1 (0.72) | GSK3AGSK3BGAANTRK1IGF1R | |
| SCHEMBL3907921 | 0.72 | GSK3A (0.47) | GSK3AGSK3BGAANTRK1IGF1R | |
| SCHEMBL29323648 | 0.72 | GSK3A (0.47) | GSK3AGSK3BGAANTRK1IGF1R | |
| SCHEMBL13562509 | 0.72 | PGR (0.51) | GSK3AGSK3BGAANTRK1IGF1R | |
| SCHEMBL265665 | 0.72 | GAA (0.50) | GSK3AGSK3BGAANTRK1IGF1R | |
| SCHEMBL13562510 | 0.71 | PGR (0.53) | GSK3AGSK3BGAANTRK1IGF1R | |
| SCHEMBL3906792 | 0.71 | GSK3A (0.46) | GSK3AGSK3BGAANTRK1IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101500534-A | Compositions comprising betulonic acid | VALTION TEKNILLINEN (FI) | 2009-08-05 | — | — | CN | claimed |
| EP-2037872-A2 | COMPOSITIONS COMPRISING BETULONIC ACID | Valtion Teknillinen Tutkimuskeskus (FI) | 2009-03-25 | — | — | EP | claimed |
| EP-2024384-A1 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIPROTOZOAL AGENTS | Valtion Teknillinen Tutkimuskeskus (FI) | 2009-02-18 | — | — | EP | claimed |
| WO-2007141391-A1 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIPROTOZOAL AGENTS | VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) | 2007-12-13 | — | — | WO | claimed |
| WO-2007141392-A2 | COMPOSITIONS COMPRISING BETULONIC ACID | VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) | 2007-12-13 | — | — | WO | claimed |
| CN-101500534-A | Compositions comprising betulonic acid | VALTION TEKNILLINEN (FI) | 2009-08-05 | — | — | CN | disclosed |
| EP-2024385-A1 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | Valtion Teknillinen Tutkimuskeskus (FI) | 2009-02-18 | — | — | EP | disclosed |
| EP-2024384-A1 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIPROTOZOAL AGENTS | Valtion Teknillinen Tutkimuskeskus (FI) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007141391-A1 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIPROTOZOAL AGENTS | VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) | 2007-12-13 | — | — | WO | disclosed |
| WO-2007141389-A1 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) | 2007-12-13 | — | — | WO | disclosed |