Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Perchlorate SCHEMBL3904907 | 0.87 | ALDH1A1 (0.38) | ALDH1A1TSHRMEN1LMNAKMT2A | |
| Tert-Butylamine SCHEMBL8359529 | 0.81 | — | — | |
| Sulfuric Acid SCHEMBL3897189 | 0.80 | TP53 (0.38) | ALDH1A1TSHR | |
| Alcohol SCHEMBL4825054 | 0.77 | — | — | |
| Tert-Butylamine SCHEMBL28718142 | 0.77 | — | — | |
| Propane SCHEMBL27940504 | 0.76 | TSHR (0.39) | TSHR | |
| Alcohol SCHEMBL28142284 | 0.71 | — | — | |
| Bromide SCHEMBL21245499 | 0.71 | — | — | |
| Bromide SCHEMBL5859172 | 0.71 | — | — | |
| Alcohol SCHEMBL27658536 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773866-A4 | USE OF METAL COMPLEXES | BIO LAYER PTY LTD (AU) | 2009-04-01 | — | — | EP | disclosed |
| EP-1773866-A1 | USE OF METAL COMPLEXES | Bio-Layer Pty Limited (AU) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006002472-A1 | USE OF METAL COMPLEXES | BIO-LAYER PTY LTD (AU) | 2006-01-12 | — | — | WO | disclosed |