⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3911224 | 1.00 | — | — | |
| SCHEMBL197640 | 1.00 | — | — | |
| Chloroform SCHEMBL29017622 | 0.80 | LMNA (0.36) | — | |
| SCHEMBL6915492 | 0.80 | — | — | |
| SCHEMBL64269 | 0.78 | — | — | |
| Acetone SCHEMBL5358085 | 0.78 | — | — | |
| Acetic Acid SCHEMBL5093045 | 0.78 | — | — | |
| SCHEMBL11718841 | 0.77 | TSHR (0.33) | — | |
| Acetone SCHEMBL27831020 | 0.77 | LMNA (0.43) | — | |
| Acetic Acid SCHEMBL11765747 | 0.77 | LMNA (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9643984-B2 | Method for the preparation of [1,2,4]-triazolo[4,3-a]pyridines | AMGEN INC. (US) | 2017-05-09 | — | — | US | disclosed |
| US-20160347769-A1 | METHOD FOR THE PREPARATION OF [1,2,4]-TRIAZOLO[4,3-A]PYRIDINES | AMGEN INC. | 2016-12-01 | — | — | US | disclosed |
| CN-105636978-A | Linear peptide antibiotics | RQX PHARMACEUTICALS INC | 2016-06-01 | — | — | CN | disclosed |
| US-20090148917-A1 | METHOD FOR PRODUCING CHIRAL ALCOHOLS | IEP GMBH (DE) | 2009-06-11 | — | — | US | disclosed |
| EP-1805313-A1 | METHOD FOR PRODUCING CHIRAL ALCOHOLS | IEP GmbH (DE) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006045598-A1 | METHOD FOR PRODUCING CHIRAL ALCOHOLS | IEP GMBH (DE) | 2006-05-04 | — | — | WO | disclosed |