SCHEMBL39111

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Bicarbonate SCHEMBL21836081	0.98	GABRA1 (0.63)	GABRA1GABRB2HMGB1ALDH1A1HPGD
	Bicarbonate SCHEMBL236892	0.98	GABRA1 (0.63)	GABRA1GABRB2HMGB1ALDH1A1HPGD
	SCHEMBL2165949	0.87	GABRA1 (0.50)	GABRA1GABRB2HMGB1ALDH1A1HPGD
	SCHEMBL1552387	0.85	HMGB1 (0.53)	GABRA1GABRB2HMGB1ALDH1A1HPGD
	SCHEMBL23642840	0.83	HMGB1 (0.51)	GABRA1GABRB2HMGB1ALDH1A1HPGD
	SCHEMBL28460329	0.83	GABRA1 (0.58)	GABRA1GABRB2HMGB1KDM4EHSD17B10
	SCHEMBL23642833	0.83	HMGB1 (0.51)	GABRA1GABRB2HMGB1ALDH1A1HPGD
	SCHEMBL157592	0.83	FOLH1 (0.53)	GABRA1GABRB2HMGB1ALDH1A1HPGD
	SCHEMBL10782179	0.83	HMGB1 (0.54)	GABRA1GABRB2HMGB1ALDH1A1HPGD
	SCHEMBL5172249	0.83	HMGB1 (0.63)	GABRA1GABRB2HMGB1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.