Sulfuric Acid

Sulfuric Acid

SCHEMBL391202

O=S(=O)(O)O.c1cc2c3cccc-2c3c1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.46
TSHR P16473 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
CA5A P35218 1/20 0.43
CA5B Q9Y2D0 1/20 0.43
CDK2 P24941 1/20 0.42
PADI4 Q9UM07 1/20 0.40
AURKA O14965 1/20 0.39
AURKB Q96GD4 1/20 0.39
TDP1 Q9NUW8 3/20 0.39
ALDH1A1 P00352 3/20 0.39
HSD17B10 Q99714 3/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
KDM4E B2RXH2 2/20 0.38
ALOX12 P18054 1/20 0.38
APEX1 P27695 1/20 0.38
LDHA P00338 1/20 0.37
ALPL P05186 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL391429 0.80 SMN1; SMN2 (0.46) TTRTSHRSMN1; SMN2CA5ACA5B
Sulfuric Acid SCHEMBL8642510 0.80 TTR (0.72) TTRTSHRAURKAAURKBTDP1
Sulfuric Acid SCHEMBL4071142 0.80 TTR (0.72) TTRSMN1; SMN2CDK2AURKAAURKB
Triphenylene SCHEMBL28892483 0.80 TDP1 (0.58) TSHRSMN1; SMN2PADI4TDP1ALDH1A1
Sulfuric Acid SCHEMBL9820211 0.76 SMN1; SMN2 (0.42) TTRTSHRSMN1; SMN2PADI4ALDH1A1
SCHEMBL6242 0.76 TTR (0.75) TTRSMN1; SMN2CDK2AURKAAURKB
SCHEMBL30233642 0.76 TTR (0.75) TTRSMN1; SMN2CDK2AURKAAURKB
SCHEMBL29363198 0.76 TTR (0.75) TTRSMN1; SMN2CDK2AURKAAURKB
Ammonia Solution, Strong SCHEMBL25312340 0.74 TTR (0.72) TTRSMN1; SMN2CDK2AURKAAURKB
SCHEMBL599986 0.74 TTR (0.72) TTRSMN1; SMN2CDK2AURKAAURKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100095781-A1 COMPLIANT AND WIRELESS HEALTH MONITORING SENSORS FOR COMPOSITE STRUCTURES LUMIMOVE, INC., D/B/A CROSSLINK (US) 2010-04-22 US claimed
US-20130280510-A1 FLEXIBLE ELECTROLUMINESCENT DEVICES AND SYSTEMS BRUTON ERIC A (US) 2013-10-24 US disclosed
US-8339040-B2 Flexible electroluminescent devices and systems LUMIMOVE, INC. (US) 2012-12-25 US disclosed
US-8100020-B2 Compliant and wireless health monitoring sensors for composite structures Lumimove, Inc., a Missouri Corporation (US) 2012-01-24 US disclosed
EP-2297559-A2 COMPLIANT AND WIRELESS HEALTH MONITORING SENSORS FOR COMPOSITE STRUCTURES Lumimove, Inc., Dba Crosslink (US) 2011-03-23 EP disclosed
EP-2227512-A1 FLEXIBLE ELECTROLUMINESCENT DEVICES AND SYSTEMS Lumimove, Inc., Dba Crosslink (US) 2010-09-15 EP disclosed
US-20100095781-A1 COMPLIANT AND WIRELESS HEALTH MONITORING SENSORS FOR COMPOSITE STRUCTURES LUMIMOVE, INC., D/B/A CROSSLINK (US) 2010-04-22 US disclosed
WO-2009155367-A2 COMPLIANT AND WIRELESS HEALTH MONITORING SENSORS FOR COMPOSITE STRUCTURES LUMIMOVE, INC., D/B/A CROSSLINK (US) 2009-12-23 WO disclosed
US-20090212690-A1 Flexible electroluminescent devices and systems LUMIMOVE, INC., D/B/A CROSSLINK (US) 2009-08-27 US disclosed
WO-2009079004-A1 FLEXIBLE ELECTROLUMINESCENT DEVICES AND SYSTEMS LUMIMOVE, INC., DBA CROSSLINK (US) 2009-06-25 WO disclosed
US-5278213-A Low viscosity solution ALLIED SIGNAL INC. (US) 1994-01-11 US disclosed
US-5254633-A Coating surface of nonconductive polymer particles with electrically conductive polymer, dispersing in nonconductive polymer ALLIED SIGNAL INC. (US) 1993-10-19 US disclosed
EP-0563289-A1 METHOD OF PROCESSING ELECTRICALLY CONDUCTIVE POLYANILINES IN SOLVENT MIXTURES AlliedSignal Inc. (US) 1993-10-06 EP disclosed
US-5227092-A Polyanilines ALLIED-SIGNAL INC. (US) 1993-07-13 US disclosed
US-5225495-A Polyanilines Stewart, II, Richard C. (US) 1993-07-06 US disclosed
WO-1993001229-A1 CONDUCTIVE POLYMER FILM FORMATION USING INITIATOR PRETREATMENT ALLIED-SIGNAL INC. (US) 1993-01-21 WO disclosed
US-5171478-A Doping with organic acids or salts; electroconductive ALLIED-SIGNAL INC. (US) 1992-12-15 US disclosed
US-5160457-A Dopes, fibers, films, moldings, sheets ALLIED-SIGNAL INC. (US) 1992-11-03 US disclosed
WO-1992015632-A1 THERMALLY INDUCED CHAIN COUPLING IN SOLID STATE POLYANILINE ALLIED-SIGNAL INC. (US) 1992-09-17 WO disclosed
WO-1992011644-A1 METHOD OF PROCESSING ELECTRICALLY CONDUCTIVE POLYANILINES IN SOLVENT MIXTURES ALLIED-SIGNAL INC. (US) 1992-07-09 WO disclosed