SCHEMBL3912852

SCHEMBL3912852

CCCCCC(C)(CC)C(C)CC.CCCCCCCC(CC)CC

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
ALDH1A1 P00352 3/20 0.34
TDP1 Q9NUW8 1/20 0.34
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
ADH1B P00325 1/20 0.33
ADH1C P00326 1/20 0.33
ADH1A P07327 1/20 0.33
ADH4 P08319 1/20 0.33
ADH7 P40394 1/20 0.33
OPRM1 P35372 1/20 0.32
SPHK1 Q9NYA1 1/20 0.32
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
PRSS3 P35030 1/20 0.31
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19687899 0.74 SMPD1 (0.37) ALDH1A1TSHR
SCHEMBL8918966 0.74 LMNA (0.62) LMNAALDH1A1TDP1CYP3A4TSHR
SCHEMBL8381849 0.74 LMNA (0.62) LMNAALDH1A1TDP1CYP3A4TSHR
SCHEMBL19179154 0.74 LMNA (0.62) LMNAALDH1A1TDP1CYP3A4TSHR
SCHEMBL1769415 0.74 LMNA (0.62) LMNAALDH1A1TDP1CYP3A4TSHR
SCHEMBL9204296 0.74 LMNA (0.62) LMNAALDH1A1TDP1CYP3A4TSHR
SCHEMBL3401826 0.74 LMNA (0.62) LMNAALDH1A1TDP1CYP3A4TSHR
SCHEMBL642658 0.74 LMNA (0.62) LMNAALDH1A1TDP1CYP3A4TSHR
SCHEMBL10582402 0.74 LMNA (0.62) LMNAALDH1A1TDP1CYP3A4TSHR
SCHEMBL10422686 0.74 LMNA (0.62) LMNAALDH1A1TDP1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2027174-A1 BRANCHED POLYOLS HAVING A STATISTICAL AVERAGE OF TWO OR MORE HYDROXYL GROUPS IN THE MOLECULE, PROCESS FOR THEIR PREPARATION AND USE THEREOF BASF Coatings AG (DE) 2009-02-25 EP disclosed
WO-2007131674-A1 BRANCHED POLYOLS HAVING A STATISTICAL AVERAGE OF TWO OR MORE HYDROXYL GROUPS IN THE MOLECULE, PROCESS FOR THEIR PREPARATION AND USE THEREOF BASF COATINGS AG (DE) 2007-11-22 WO disclosed