Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 18/20 | 0.35 |
| ▸ | KIT | P10721 | 3/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4185711 | 0.91 | CSF1R (0.38) | CSF1RKITTBK1 | |
| SCHEMBL3910301 | 0.80 | CSF1R (0.33) | CSF1RKIT | |
| SCHEMBL3083255 | 0.75 | CSF1R (0.40) | CSF1RKITTBK1 | |
| SCHEMBL4848346 | 0.74 | ALDH1A1 (0.42) | — | |
| SCHEMBL3087574 | 0.72 | ALDH1A1 (0.40) | CSF1RTBK1 | |
| SCHEMBL3087473 | 0.72 | CSF1R (0.50) | CSF1RKIT | |
| SCHEMBL3082933 | 0.72 | CSF1R (0.46) | CSF1RKIT | |
| SCHEMBL3088771 | 0.71 | CSF1R (0.41) | CSF1RKIT | |
| SCHEMBL4188951 | 0.71 | CSF1R (0.39) | CSF1RKIT | |
| SCHEMBL4181733 | 0.71 | CSF1R (0.56) | CSF1RKITTBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2016057-A1 | C-FMS KINASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-01-21 | — | — | EP | disclosed |
| WO-2007123516-A1 | C-FMS KINASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-11-01 | — | — | WO | disclosed |