Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | FKBP1A | P62942 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20993944 | 0.96 | MMEL1 (0.65) | POLBMMEL1MEN1KMT2AALDH1A1 | |
| SCHEMBL19880370 | 0.87 | SMN1; SMN2 (0.51) | POLBMMEL1ALDH1A1SMN1; SMN2FKBP1A | |
| SCHEMBL19880369 | 0.87 | SMN1; SMN2 (0.51) | POLBMMEL1ALDH1A1SMN1; SMN2FKBP1A | |
| SCHEMBL18734805 | 0.87 | SMN1; SMN2 (0.51) | POLBMMEL1ALDH1A1SMN1; SMN2FKBP1A | |
| SCHEMBL934366 | 0.86 | MMEL1 (0.58) | POLBMMEL1ALDH1A1FKBP1ATSHR | |
| SCHEMBL2707345 | 0.86 | MMEL1 (0.58) | POLBMMEL1ALDH1A1FKBP1ATSHR | |
| SCHEMBL1627052 | 0.84 | MEN1 (0.77) | POLBMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL10881324 | 0.83 | MMEL1 (0.60) | POLBMMEL1FKBP1A | |
| SCHEMBL14836855 | 0.83 | MMEL1 (0.52) | MMEL1ALDH1A1SMN1; SMN2FKBP1AMAPK1 | |
| SCHEMBL12999748 | 0.81 | MMEL1 (0.63) | POLBMMEL1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| EP-2017263-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2009-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | S1PR3, S1PR2, S1PR1 | POLB 4511/4885MMEL1 2729/4885MEN1 1522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.