SCHEMBL3913159

SCHEMBL3913159

Cc1cn([C@H]2C[C@H](ONC(=O)OCC3c4ccccc4-c4ccccc43)[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.61

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.61
TK1 P04183 7/20 0.48
TK2 O00142 4/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3919896 0.87 POLB (0.55) RNASE1TK1
SCHEMBL8725738 0.82
SCHEMBL14718793 0.80 RNASE1 (0.52) RNASE1TK1TK2
SCHEMBL5167159 0.80 POLB (0.54) RNASE1
SCHEMBL5163557 0.79 RNASE1 (0.53) RNASE1TK1TK2
SCHEMBL13401338 0.79 RNASE1 (0.48) RNASE1TK1TK2
SCHEMBL8583349 0.78 RNASE1 (0.51) RNASE1TK1TK2
SCHEMBL10489355 0.78 RNASE1 (0.47) RNASE1
SCHEMBL16704351 0.77 RNASE1 (0.71) RNASE1TK1TK2
SCHEMBL1334035 0.77 RNASE1 (0.71) RNASE1TK1TK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7544794-B1 Method for sequencing DNA and RNA by synthesis BENNER STEVEN ALBERT 2009-06-09 US disclosed