Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.58 |
| ▸ | CYCS | P99999 | 3/20 | 0.56 |
| ▸ | TERT | O14746 | 5/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | STAT1 | P42224 | 1/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3912287 | 1.00 | TOP1 (0.58) | TOP1CYCSTERTSTAT3STAT1 | |
| SCHEMBL10141414 | 1.00 | TOP1 (0.58) | TOP1CYCSTERTSTAT3STAT1 | |
| SCHEMBL3912280 | 1.00 | TOP1 (0.58) | TOP1CYCSTERTSTAT3STAT1 | |
| SCHEMBL29693624 | 0.93 | TERT (0.62) | TOP1CYCSTERTENPP2ABCG2 | |
| SCHEMBL242168 | 0.93 | TERT (0.62) | TOP1CYCSTERTENPP2ABCG2 | |
| SCHEMBL6883584 | 0.93 | TOP1 (0.51) | TOP1CYCSTERTSTAT3STAT1 | |
| SCHEMBL25407804 | 0.91 | TERT (0.65) | TOP1CYCSTERTENPP2ABCG2 | |
| SCHEMBL31182124 | 0.91 | TERT (0.60) | TOP1CYCSTERTENPP2ABCG2 | |
| SCHEMBL31040346 | 0.91 | TERT (0.60) | TOP1CYCSTERTENPP2ABCG2 | |
| SCHEMBL31375135 | 0.91 | TERT (0.60) | TOP1CYCSTERTENPP2ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220416167-A1 | OSMIUM-CONTAINING CONJUGATED POLYMER AND METHODS THEREOF | XIAMEN UNIVERSITY (CN) | 2022-12-29 | — | — | US | disclosed |
| WO-2021143690-A1 | OSMIUM-CONTAINING CONJUGATED POLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF | 厦门大学 | 2021-07-22 | — | — | WO | disclosed |
| US-8431117-B2 | Sickled erythrocytes with anti-tumor agents induce tumor vaso-occlusion and tumoricidal effects | TERMAN DAVID S (US) | 2013-04-30 | — | — | US | disclosed |
| US-20120195869-A1 | Sickled Erythrocytes with Anti-tumor Agents Induce Tumor Vaso-occlusion and Tumoricidal Effects | TERMAN DAVID S (US) | 2012-08-02 | — | — | US | disclosed |
| US-7595407-B2 | Boron complexation strategy for use in manipulating 1-acyldipyrromethanes | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-09-29 | — | — | US | disclosed |
| US-7595407-B2 | Boron complexation strategy for use in manipulating 1-acyldipyrromethanes | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-09-29 | — | — | US | disclosed |
| US-7595407-B2 | Boron complexation strategy for use in manipulating 1-acyldipyrromethanes | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-09-29 | — | — | US | disclosed |
| US-7423160-B2 | Boron complexation strategy for use in manipulating 1-acyldipyrromethanes | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-09-09 | — | — | US | disclosed |
| US-7423160-B2 | Boron complexation strategy for use in manipulating 1-acyldipyrromethanes | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-09-09 | — | — | US | disclosed |
| US-7423160-B2 | Boron complexation strategy for use in manipulating 1-acyldipyrromethanes | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-09-09 | — | — | US | disclosed |
| US-20070088158-A1 | BORON COMPLEXATION STRATEGY FOR USE IN MANIPULATING 1-ACYLDIPYRROMETHANES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-04-19 | — | — | US | disclosed |
| US-20070088158-A1 | BORON COMPLEXATION STRATEGY FOR USE IN MANIPULATING 1-ACYLDIPYRROMETHANES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-04-19 | — | — | US | disclosed |
| US-20070088158-A1 | BORON COMPLEXATION STRATEGY FOR USE IN MANIPULATING 1-ACYLDIPYRROMETHANES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-04-19 | — | — | US | disclosed |
| US-7153975-B2 | Boron complexation strategy for use in manipulating 1-acyldipyrromethanes | NORTH CAROLINA STATE UNIVERSITY (US) | 2006-12-26 | — | — | US | disclosed |
| US-20050282778-A1 | Boron complexation strategy for use in manipulating 1-acyldipyrromethanes | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-12-22 | — | — | US | disclosed |
| US-20050282779-A1 | Boron complexation strategy for use in manipulating 1-acyldipyrromethanes | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-12-22 | — | — | US | disclosed |
| US-6924375-B2 | Facile synthesis of 1,9-diacyldipyrromethanes | NORTH CAROLINA STATE UNIVERSITY (US) | 2005-08-02 | — | — | US | disclosed |
| US-20050054858-A1 | Facile synthesis of 1,9-diacyldipyrromethanes | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2005-03-10 | — | — | US | disclosed |
| US-6849730-B2 | Methods of making porphyrins and related compounds with Lewis acids | NORTH CAROLINA STATE UNIVERSITY (US) | 2005-02-01 | — | — | US | disclosed |
| US-20030096978-A1 | Methods of making porphyrins and related compounds with Lewis acids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282778-A1 | Boron complexation strategy for use in manipulating 1-acyldipyrromethanes | DECR2, ANTXR2, CD79B | TOP1 2422/4885CYCS 2446/4885TERT 3476/4885 |
| US-20050282779-A1 | Boron complexation strategy for use in manipulating 1-acyldipyrromethanes | DECR2, ANTXR2, CD79B | TOP1 2422/4885CYCS 2446/4885TERT 3476/4885 |
| US-20070088158-A1 | BORON COMPLEXATION STRATEGY FOR USE IN MANIPULATING 1-ACYLDIPYRROMETHANES | DECR2, ANTXR2, CD79B | TOP1 2422/4885CYCS 2446/4885TERT 3476/4885 |
| US-20050054858-A1 | Facile synthesis of 1,9-diacyldipyrromethanes | GLI2, DKC1, NR2F2 | TOP1 391/4885CYCS 1648/4885TERT 760/4885 |
| US-20030096978-A1 | Methods of making porphyrins and related compounds with Lewis acids | DDT, LIG3, SHARPIN | TOP1 1009/4885CYCS 372/4885TERT 374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.