Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 11/20 | 0.47 |
| ▸ | CA2 | P00918 | 11/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31299566 | 0.98 | CA1 (0.48) | CA1CA2CA9JAK2JAK3 | |
| SCHEMBL575913 | 0.89 | CA2 (0.51) | CA1CA2CA9JAK2JAK3 | |
| Biphenyl SCHEMBL3395019 | 0.88 | PIK3CD (0.45) | CA1CA2CA9JAK2JAK3 | |
| Diphenylsulfane SCHEMBL18863901 | 0.85 | PIK3CD (0.41) | CA1CA2CA9JAK2JAK3 | |
| SCHEMBL575757 | 0.83 | CA2 (0.46) | CA1CA2CA9JAK2JAK3 | |
| Hydrogen Sulfide SCHEMBL5680921 | 0.83 | CA1 (0.47) | CA1CA2CA9JAK2JAK3 | |
| Iodide SCHEMBL5315919 | 0.82 | PIK3CD (0.44) | CA1CA2CA9JAK2JAK3 | |
| SCHEMBL31299570 | 0.82 | CA2 (0.47) | CA1CA2CA9JAK2JAK3 | |
| SCHEMBL24634528 | 0.81 | CA2 (0.55) | CA1CA2CA9PPARGCA5A | |
| SCHEMBL9966117 | 0.81 | CA1 (0.46) | CA1CA2CA9PPARGCA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1840650-B1 | Positive type radiation-sensitive resin composition | JSR CORP (JP) | 2009-03-18 | — | — | EP | disclosed |
| EP-1840650-A1 | Positive type radiation-sensitive resin composition | JSR Corporation (JP) | 2007-10-03 | — | — | EP | disclosed |