SCHEMBL3915092

SCHEMBL3915092

COC(=O)NSSNC(=O)OC.[Zn]

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32
TSHR P16473 1/20 0.32
GLA P06280 1/20 0.31
EPHX1 P07099 1/20 0.31
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11443761 0.97 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2KEAP1NFE2L2HCAR2
SCHEMBL25962038 0.79
SCHEMBL29625259 0.78 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2KEAP1NFE2L2HCAR2
SCHEMBL11495842 0.75
SCHEMBL19935597 0.73
SCHEMBL2107953 0.69
SCHEMBL8888479 0.69 ALDH1A1 (0.32) ALDH1A1
SCHEMBL11570309 0.67
SCHEMBL4138400 0.67
SCHEMBL11056390 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534828-B2 e.g.natural rubber, neoprene, polyisoprene, butyl rubber, polybutadiene, styrene-butadiene copolymer as unsaturated elastomers; filler selected from carbon black and silica; N,N'-(m-phenylene)bismaleamic acid, zinc dibenzyl dithiocarbamate, a cure accelerators THE GOODYEAR TIRE & RUBBER COMPANY (US) 2009-05-19 US disclosed
EP-1801150-A1 Pneumatic tire having a rubber component containing N,N'-(m-phenylene) bismaleamic acid or N,N'-(m-phenylene) bismaleimide THE GOODYEAR TIRE & RUBBER COMPANY (US) 2007-06-27 EP disclosed
US-20070142508-A1 e.g.natural rubber, neoprene, polyisoprene, butyl rubber, polybutadiene, styrene-butadiene copolymer as unsaturated elastomers; filler selected from carbon black and silica; N,N'-(m-phenylene)bismaleamic acid, zinc dibenzyl dithiocarbamate, a cure accelerators THE GOODYEAR TIRE & RUBBER COMPANY 2007-06-21 US disclosed
CN-1173628-C Pesticide compositions ������������� 2004-11-03 CN disclosed
CN-1195472-A Pesticide compositions ROHM & HAAS (US) 1998-10-14 CN disclosed