Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 14/20 | 0.60 |
| ▸ | MMP13 | P45452 | 15/20 | 0.47 |
| ▸ | MMP9 | P14780 | 8/20 | 0.47 |
| ▸ | MMP2 | P08253 | 6/20 | 0.47 |
| ▸ | MMP14 | P50281 | 5/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | BMP1 | P13497 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 3/20 | 0.40 |
| ▸ | MMP8 | P22894 | 3/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP10 | P09238 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3920825 | 0.99 | MMP1 (0.59) | MMP1MMP13MMP9MMP2MMP14 | |
| SCHEMBL3916840 | 0.98 | MMP1 (0.63) | MMP1MMP13MMP9MMP2MMP14 | |
| SCHEMBL13899017 | 0.90 | MMP1 (0.52) | MMP1MMP13MMP9MMP2MMP14 | |
| SCHEMBL3914710 | 0.88 | MMP1 (0.78) | MMP1MMP13MMP9MMP2MMP14 | |
| SCHEMBL3923541 | 0.88 | MMP1 (0.60) | MMP1MMP13MMP9MMP2MMP14 | |
| SCHEMBL3913267 | 0.88 | MMP1 (0.55) | MMP1MMP13MMP9MMP2MMP14 | |
| SCHEMBL3922883 | 0.87 | MMP1 (0.56) | MMP1MMP13MMP9MMP2MMP14 | |
| SCHEMBL3913080 | 0.87 | MMP1 (0.59) | MMP1MMP13MMP9MMP2MMP14 | |
| SCHEMBL3923765 | 0.86 | MMP1 (0.66) | MMP1MMP13MMP9MMP2MMP14 | |
| SCHEMBL3914343 | 0.86 | MMP1 (0.60) | MMP1MMP13MMP9MMP2MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504537-B2 | Hydroxamic acid derivative and MMP inhibitor containing the same as active ingredient | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |
| US-7504537-B2 | Hydroxamic acid derivative and MMP inhibitor containing the same as active ingredient | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |
| US-7504537-B2 | Hydroxamic acid derivative and MMP inhibitor containing the same as active ingredient | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |