SCHEMBL3915264

SCHEMBL3915264

CO[Si](CCCC1CCCN1)(OC)OC

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CHRNA3 P32297 7/20 0.40
CHRNB4 P30926 5/20 0.40
HRH3 Q9Y5N1 2/20 0.38
CHRNB2 P17787 2/20 0.35
CHRNA4 P43681 1/20 0.35
CHRNA5 P30532 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HIF1A Q16665 1/20 0.33
PHLPP2 Q6ZVD8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3909852 0.95 HRH3 (0.43) CHRNA3CHRNB4HRH3CYP1A2CYP2D6
SCHEMBL3909210 0.89 CHRNA3 (0.41) CHRNA3CHRNB4HRH3CHRNB2CHRNA4
SCHEMBL3919056 0.84 HRH3 (0.37) CHRNA3CHRNB4HRH3CHRNB2CHRNA4
SCHEMBL3917853 0.84 HRH3 (0.41) CHRNA3CHRNB4HRH3CYP1A2CYP2D6
SCHEMBL3912530 0.83 HRH3 (0.36) CHRNA3CHRNB4HRH3CHRNB2CHRNA4
SCHEMBL16714870 0.79 HRH3 (0.42) CHRNA3CHRNB4HRH3CHRNB2CHRNA5
SCHEMBL3912128 0.79 HRH3 (0.42) CHRNA3CHRNB4HRH3CHRNB2CHRNA5
SCHEMBL3910872 0.78 HRH3 (0.41) HRH3CYP1A2CYP2D6CYP2C19SMN1; SMN2
SCHEMBL29270359 0.77 CXCR4 (0.38)
SCHEMBL27858197 0.77 CHRNA3 (0.40) CHRNA3CHRNB4CHRNB2CHRNA4CHRNA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113024594-B Preparation method of 1, 1-dimethoxy-1-silicon-2- (3- (trimethoxysilyl) propyl) azacyclopentane 张家港市国泰华荣化工新材料有限公司 2022-05-24 CN claimed
CN-113024594-B Preparation method of 1, 1-dimethoxy-1-silicon-2- (3- (trimethoxysilyl) propyl) azacyclopentane 张家港市国泰华荣化工新材料有限公司 2022-05-24 CN disclosed
CN-113024594-B Preparation method of 1, 1-dimethoxy-1-silicon-2- (3- (trimethoxysilyl) propyl) azacyclopentane 张家港市国泰华荣化工新材料有限公司 2022-05-24 CN disclosed
CN-113024594-B Preparation method of 1, 1-dimethoxy-1-silicon-2- (3- (trimethoxysilyl) propyl) azacyclopentane 张家港市国泰华荣化工新材料有限公司 2022-05-24 CN disclosed
US-20090277559-A1 METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-11-12 US disclosed
EP-1840158-B1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2009-02-18 EP disclosed