Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tabun SCHEMBL30409655 | 1.00 | ACHE (1.00) | ACHETSHRTP53TDP1LMNA | |
| Tabun SCHEMBL60863 | 1.00 | ACHE (1.00) | ACHETSHRTP53TDP1LMNA | |
| Tabun SCHEMBL29644762 | 0.98 | ACHE (0.96) | ACHETSHRTP53TDP1LMNA | |
| Tabun SCHEMBL29676743 | 0.98 | ACHE (0.96) | ACHETSHRTP53TDP1LMNA | |
| Tabun SCHEMBL29828654 | 0.96 | ACHE (0.92) | ACHETSHRTP53TDP1LMNA | |
| Tabun SCHEMBL7874201 | 0.89 | ACHE (0.79) | ACHETSHRTP53TDP1LMNA | |
| Tabun SCHEMBL29583505 | 0.83 | ACHE (0.69) | ACHETSHRPPARD | |
| SCHEMBL13412912 | 0.83 | ACHE (0.70) | ACHETSHRKMT2AMEN1 | |
| Tabun SCHEMBL9292835 | 0.82 | ACHE (0.67) | ACHELMNAKMT2AALDH1A1MEN1 | |
| Tabun SCHEMBL1976996 | 0.82 | ACHE (0.67) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101500600-A | Methods for ester detoxication | HUMAN BIOMOLECULAR RES INST (US) | 2009-08-05 | — | — | CN | disclosed |
| EP-2035032-A2 | METHODS FOR ESTER DETOXICATION | Human Biomolecular Research Institute (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007146003-A2 | METHODS FOR ESTER DETOXICATION | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2007-12-21 | — | — | WO | disclosed |
| WO-2004108172-A1 | METAL OXIDE DECONTAMINATION OF WARFARE AGENTS | NANOSCALE MATERIALS, INC. (US) | 2004-12-16 | — | — | WO | disclosed |
| WO-2004053891-A2 | SYSTEM FOR CONTROL OF CHEMICAL / BIOLOGICAL WARFARE AGENTS | NANOSCALE MATERIALS, INC. (US) | 2004-06-24 | — | — | WO | disclosed |