Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.57 |
| ▸ | ACE | P12821 | 3/20 | 0.57 |
| ▸ | RIPK1 | Q13546 | 11/20 | 0.54 |
| ▸ | XIAP | P98170 | 5/20 | 0.52 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3913698 | 0.90 | RIPK1 (0.64) | MMEACERIPK1XIAPNPY1R | |
| SCHEMBL12345873 | 0.85 | RIPK1 (0.49) | MMEACERIPK1XIAP | |
| SCHEMBL3910591 | 0.84 | RIPK1 (0.68) | RIPK1NR1I2CYP2C9 | |
| SCHEMBL3910585 | 0.84 | RIPK1 (0.68) | RIPK1NR1I2CYP2C9 | |
| SCHEMBL3914724 | 0.82 | MME (0.53) | MMEACERIPK1XIAPNPY1R | |
| SCHEMBL3912421 | 0.79 | XIAP (0.55) | MMEACERIPK1XIAPNPY1R | |
| SCHEMBL3911195 | 0.78 | SCN9A (0.51) | MMEACERIPK1XIAPNPY1R | |
| SCHEMBL12345874 | 0.77 | SCN9A (0.42) | MMEACERIPK1XIAP | |
| SCHEMBL7341191 | 0.76 | MME (0.62) | MMEACERIPK1XIAPNPY1R | |
| SCHEMBL7341195 | 0.76 | MME (0.62) | MMEACERIPK1XIAPNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029555-A2 | DERIVATIVES OF 2-ALKOXY-3,4,5-TRIHYDROXY-ALKYL AMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THE SAME | Sanofi-Aventis (FR) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007135295-A2 | DERIVATIVES OF 2-ALKOXY-3,4,5-TRIHYDROXY-ALKYL AMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THE SAME | SANOFI-AVENTIS (FR) | 2007-11-29 | — | — | WO | disclosed |