SCHEMBL3916941

SCHEMBL3916941

COCCOCCO[Si](CCCOC(=O)Cc1ccncc1)(OCCOCCOC)OCCOCCOC

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 13/20 0.50
LMNA P02545 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TSHR P16473 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
NAMPT P43490 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3914292 0.93 CYP19A1 (0.52) CYP19A1LMNASMN1; SMN2ALDH1A1GAA
SCHEMBL3908881 0.86 CYP19A1 (0.50) CYP19A1SMN1; SMN2
SCHEMBL3912637 0.83 CYP19A1 (0.56) CYP19A1LMNASMN1; SMN2TSHRL3MBTL1
SCHEMBL3910867 0.83 CYP19A1 (0.58) CYP19A1LMNASMN1; SMN2TSHRL3MBTL1
SCHEMBL3914955 0.82 CYP3A4 (0.45) LMNASMN1; SMN2TSHRL3MBTL1ALDH1A1
SCHEMBL3909271 0.80 HPGD (0.41) SMN1; SMN2TSHRL3MBTL1ALDH1A1
SCHEMBL3912022 0.77 CYP19A1 (0.57) CYP19A1LMNASMN1; SMN2TSHRL3MBTL1
SCHEMBL3910817 0.75 CYP19A1 (0.58) CYP19A1LMNASMN1; SMN2
SCHEMBL3916939 0.75 CYP19A1 (0.55) CYP19A1TSHRL3MBTL1ALDH1A1GAA
SCHEMBL3908831 0.74 CYP19A1 (0.61) CYP19A1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090277559-A1 METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-11-12 US disclosed
EP-1840158-B1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2009-02-18 EP disclosed