Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3908799 | 0.92 | KMT2A (0.44) | CYP3A4ABCB11ADRA2BOPRD1SCN5A | |
| SCHEMBL3910178 | 0.85 | KDM4E (0.43) | CYP3A4ABCB11ADRA2BOPRD1SCN5A | |
| SCHEMBL3916941 | 0.82 | CYP19A1 (0.50) | ALDH1A1LMNAL3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL3916946 | 0.82 | ALDH1A1 (0.47) | CYP3A4KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL3914339 | 0.82 | KMT2A (0.49) | CYP3A4KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL14919008 | 0.80 | TSHR (0.55) | CYP3A4ABCB11ADRA2BOPRD1SCN5A | |
| SCHEMBL3911551 | 0.79 | APP (0.51) | KMT2AMAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL17641405 | 0.77 | KDM4E (0.57) | KMT2AMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL3918074 | 0.75 | ALDH1A1 (0.45) | CYP3A4KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL19688301 | 0.75 | TDP1 (0.59) | CYP3A4KMT2AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090277559-A1 | METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE | BRIDGESTONE CORPORATION (JP) | 2009-11-12 | — | — | US | disclosed |
| EP-1840158-B1 | METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE | BRIDGESTONE CORP (JP) | 2009-02-18 | — | — | EP | disclosed |