SCHEMBL3917042

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3914972	0.76	ALDH1A1 (0.41)	PKMKMT2AGAAALDH1A1LMNA
	SCHEMBL3914886	0.76	ALDH1A1 (0.41)	PKMKMT2AGAAALDH1A1USP2
	SCHEMBL3916838	0.72	KMT2A (0.42)	PKMKMT2AHPGDHTTALDH1A1
	SCHEMBL1803114	0.71	CYP3A4 (0.47)	KMT2AGAAHPGDHTTALDH1A1
	SCHEMBL3918743	0.71	ALDH1A1 (0.38)	KMT2AGAAHTTALDH1A1USP2
	SCHEMBL3918416	0.71	KMT2A (0.46)	KMT2AGAAALDH1A1LMNASMN1; SMN2
	SCHEMBL3919441	0.69	TP53 (0.42)	PKMHTTALDH1A1USP2LMNA
	SCHEMBL1802881	0.69	MEN1 (0.39)	KMT2AHPGDALDH1A1USP2LMNA
	SCHEMBL3919937	0.69	GPBAR1 (0.42)	PKMKMT2AHTTALDH1A1USP2
	SCHEMBL3919446	0.69	ALDH1A1 (0.40)	KMT2AGAAHTTALDH1A1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.