⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4969215 | 0.72 | PHF8 (0.38) | — | |
| SCHEMBL23816237 | 0.69 | — | — | |
| SCHEMBL8580457 | 0.69 | — | — | |
| SCHEMBL3911474 | 0.67 | — | — | |
| SCHEMBL6498969 | 0.67 | — | — | |
| SCHEMBL14307468 | 0.67 | — | — | |
| SCHEMBL19383636 | 0.67 | — | — | |
| SCHEMBL817079 | 0.67 | — | — | |
| SCHEMBL8583300 | 0.67 | — | — | |
| SCHEMBL134099 | 0.67 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673399-B1 | DETECTING AND PROFILING MOLECULAR COMPLEXES | MONOGRAM BIOSCIENCES INC (US) | 2017-04-05 | — | — | EP | disclosed |
| US-9110075-B2 | Compositions for analyzing proteins | MONOGRAM BIOSCIENCES, INC. (US) | 2015-08-18 | — | — | US | disclosed |
| EP-2068828-A2 | BIODEGRADABLE OCULAR IMPLANTS AND METHODS FOR TREATING OCULAR CONDITIONS | SurModics, Inc. (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-2015794-A2 | HYDROPHILIC SHAPE MEMORY INSERTABLE MEDICAL ARTICLES | SurModics, Inc. (US) | 2009-01-21 | — | — | EP | disclosed |
| WO-2009005718-A1 | POLYPEPTIDE MICROPARTICLES HAVING SUSTAINED RELEASE CHARACTERISTICS, METHODS AND USES | SURMODICS, INC. (US) | 2009-01-08 | — | — | WO | disclosed |
| EP-1937327-A1 | NATURAL BIODEGRADABLE MATRICES AND USES THEREOF | SurModics, Inc. (US) | 2008-07-02 | — | — | EP | disclosed |
| WO-2008073295-A2 | LATENT STABILIZATION OF BIOACTIVE AGENTS RELEASABLE FROM IMPLANTABLE MEDICAL ARTICLES | SURMODICS, INC. (US) | 2008-06-19 | — | — | WO | disclosed |
| EP-1926505-A1 | IN VIVO FORMED MATRICES INCLUDING NATURAL BIODEGRADABLE POLYSACCHARIDES AND OPHTHALMIC USES THEREOF | SurModics, Inc. (US) | 2008-06-04 | — | — | EP | disclosed |
| EP-1926509-A1 | COATINGS AND ARTICLES INCLUDING NATURAL BIODEGRADABLE POLYSACCHARIDES | SurModics, Inc. (US) | 2008-06-04 | — | — | EP | disclosed |
| EP-1926504-A1 | COATINGS AND ARTICLES INCLUDING NATURAL BIODEGRADABLE POLYSACCHARIDES | SurModics, Inc. (US) | 2008-06-04 | — | — | EP | disclosed |
| WO-2005115490-A2 | NATURAL BIODEGRADABLE POLYSACCHARIDE COATINGS FOR MEICAL ARTICLES | SURMODICS, INC. (US) | 2005-12-08 | — | — | WO | disclosed |
| WO-2005113034-A1 | NATURAL BIODEGRADABLE POLYSACCHARIDES COATINGS FOR MEDICAL ARTICLES | SURMODICS, INC. (US) | 2005-12-01 | — | — | WO | disclosed |
| US-5827672-A | Human monocyte elastase inhibitor antibodies | CENTER FOR BLOOD RESEARCH, INC. (US) | 1998-10-27 | — | — | US | disclosed |
| EP-0460072-B1 | HUMAN ELASTASE INHIBITOR | BLOOD RES CENTER (US) | 1998-02-04 | — | — | EP | disclosed |
| US-5663299-A | Human monocyte elastase inhibitor | CENTER FOR BLOOD RESEARCH, INC. (US) | 1997-09-02 | — | — | US | disclosed |
| WO-1996010418-A1 | HUMAN MONOCYTE ELASTASE INHIBITOR | CENTER FOR BLOOD RESEARCH, INC. (US) | 1996-04-11 | — | — | WO | disclosed |
| US-5370991-A | Forms complex with elastase and inhibits elastinolytic activity of elastase | THE CENTER FOR BLOOD RESEARCH, INC. (US) | 1994-12-06 | — | — | US | disclosed |
| EP-0460072-A4 | HUMAN ELASTASE INHIBITOR | — | 1992-02-12 | — | — | EP | disclosed |
| EP-0460072-A1 | HUMAN ELASTASE INHIBITOR | CENTER FOR BLOOD RESEARCH, INC. (US) | 1991-12-11 | — | — | EP | disclosed |
| WO-1990009737-A1 | HUMAN ELASTASE INHIBITOR | THE CENTER FOR BLOOD RESEARCH (US) | 1990-09-07 | — | — | WO | disclosed |