Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.54 |
| ▸ | MMP9 | P14780 | 5/20 | 0.53 |
| ▸ | MMP1 | P03956 | 4/20 | 0.53 |
| ▸ | MMP2 | P08253 | 4/20 | 0.53 |
| ▸ | MMP3 | P08254 | 4/20 | 0.53 |
| ▸ | MMP7 | P09237 | 4/20 | 0.53 |
| ▸ | MMP13 | P45452 | 4/20 | 0.53 |
| ▸ | PLAU | P00749 | 2/20 | 0.53 |
| ▸ | HPN | P05981 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3905584 | 0.89 | MMP2 (0.54) | CAPN1MMP9MMP1MMP2MMP3 | |
| SCHEMBL3904669 | 0.89 | CAPN1 (0.66) | CAPN1MMP9MMP1MMP2MMP3 | |
| SCHEMBL5363846 | 0.89 | CAPN1 (0.66) | CAPN1MMP9MMP1MMP2MMP3 | |
| SCHEMBL1907361 | 0.89 | CAPN1 (0.66) | CAPN1MMP9MMP1MMP2MMP3 | |
| SCHEMBL3913553 | 0.89 | CAPN1 (0.66) | CAPN1MMP9MMP1MMP2MMP3 | |
| SCHEMBL6026500 | 0.89 | CAPN1 (0.66) | CAPN1MMP9MMP1MMP2MMP3 | |
| SCHEMBL3914517 | 0.84 | GAA (0.53) | CAPN1MMP9MMP1MMP2MMP3 | |
| SCHEMBL3915375 | 0.83 | CAPN1 (0.64) | CAPN1MMP9MMP1MMP2MMP3 | |
| SCHEMBL8816828 | 0.80 | PLAU (0.48) | CAPN1PLAUHPN | |
| SCHEMBL7774217 | 0.79 | CAPN1 (0.48) | CAPN1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572833-B2 | Drug composition comprising dipeptidyl aldehyde derivative | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2009-08-11 | — | — | US | disclosed |
| EP-1504760-B1 | Pharmaceutical composition for prophylaxis and therapy of diseases associated with ocular fundus tissue cytopathy | SENJU PHARMA CO (JP) | 2008-07-09 | — | — | EP | disclosed |
| US-7052714-B1 | Ophthalmic adhesive preparations for percutaneous adsorption | SENJU PHARMACEUTICAL CO., LTD (JP) | 2006-05-30 | — | — | US | disclosed |
| EP-1058553-B1 | PHARMACEUTICAL COMPOSITION FOR PROPHYLAXIS AND THERAPY OF DISEASES ASSOCIATED WITH OCULAR FUNDUS TISSUE CYTOPATHY | SENJU PHARMA CO (JP) | 2005-06-01 | — | — | EP | disclosed |
| EP-1504760-A1 | Pharmaceutical composition for prophylaxis and therapy of diseases associated with ocular fundus tissue cytopathy | Senju Pharmaceutical Co., Ltd. (JP) | 2005-02-09 | — | — | EP | disclosed |
| EP-1064021-B1 | USE OF CYSTEINPROTEASE INHIBITORS FOR THE MANUFACTURE OF A MEDICAMENT FOR PREVENTION AND TREATMENT OF BRAIN TISSUE IMPAIRMENT DUE TO HYPERTENSIVE ENCEPHALOPATHY OR ENCEPHALOTHLIPSIS. | SENJU PHARMA CO (JP) | 2004-09-08 | — | — | EP | disclosed |
| US-20040048929-A1 | Drug composition comprising dipeptidyl aldehyde derivative | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-1334718-A1 | DRUG COMPOSITION COMPRISING DIPEPTYDYL ALDEHYDE DERIVATIVE | Senju Pharmaceutical Co., Ltd. (JP) | 2003-08-13 | — | — | EP | disclosed |
| EP-0927716-B1 | Angiogenesis inhibitor | SENJU PHARMA CO (JP) | 2003-05-07 | — | — | EP | disclosed |
| US-6551999-B1 | For therapy and prophylaxis of angiogenesis associated with wound healing, inflammation, growth of tumor and the like; angiogenesis as seen in diabetic retinopathy, prematurity retinopathy, retinal venous occlusion, metastasis of tumors | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2003-04-22 | — | — | US | disclosed |
| US-6342531-B1 | ANTICOAGULANTS, HEMOSTATIC, ANTIISCHEMIC, HYPOTENSIVE, ANTITUMOR, ANTIARRHYTHMIC AGENTS | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2002-01-29 | — | — | US | disclosed |
| US-6214800-B1 | ANGIOGENESIS INHIBITORS | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-1064021-A1 | PHARMACEUTICAL COMPOSITION CONTAINING A CYSTEINE PROTEASE INHIBITOR FOR PROPHYLAXIS AND THERAPY OF BRAIN TISSUE IMPAIRMENT | Senju Pharmaceutical Co., Ltd. (JP) | 2001-01-03 | — | — | EP | disclosed |
| EP-1058553-A2 | PHARMACEUTICAL COMPOSITION FOR PROPHYLAXIS AND THERAPY OF DISEASES ASSOCIATED WITH OCULAR FUNDUS TISSUE CYTOPATHY | Senju Pharmaceutical Co., Ltd. (JP) | 2000-12-13 | — | — | EP | disclosed |
| US-6057290-A | ADMINISTERING A CYSTEINE PROTEASE INHIBITOR TO A PATIENT FOR INHIBITING ANGIOGENESIS | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| WO-1999048522-A1 | PHARMACEUTICAL COMPOSITION CONTAINING A CYSTEINE PROTEASE INHIBITOR FOR PROPHYLAXIS AND THERAPY OF BRAIN TISSUE IMPAIRMENT | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-30 | — | — | WO | disclosed |
| WO-1999044624-A2 | PHARMACEUTICAL COMPOSITION FOR PROPHYLAXIS AND THERAPY OF DISEASES ASSOCIATED WITH OCULAR FUNDUS TISSUE CYTOPATHY | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-10 | — | — | WO | disclosed |
| EP-0928786-A1 | Angiogenesis inhibitor | Senju Pharmaceutical Co., Ltd. (JP) | 1999-07-14 | — | — | EP | disclosed |
| EP-0927716-A1 | Angiogenesis inhibitor | Senju Pharmaceutical Co., Ltd. (JP) | 1999-07-07 | — | — | EP | disclosed |
| EP-0771565-A2 | Angiogenesis inhibitor | Senju Pharmaceutical Co., Ltd. (JP) | 1997-05-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040048929-A1 | Drug composition comprising dipeptidyl aldehyde derivative | DPP4, DPP3, DPP7 | CAPN1 2707/4885MMP9 589/4885MMP1 277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.