Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 5/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3915648 | 0.88 | KCNA5 (0.53) | KCNA5MEN1KMT2AATMUSP2 | |
| SCHEMBL3920496 | 0.87 | KCNA5 (0.47) | KCNA5PDE10ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3917567 | 0.85 | KCNA5 (0.49) | KCNA5MEN1KMT2APOLBMAPT | |
| SCHEMBL3925887 | 0.85 | KCNA5 (0.52) | KCNA5MEN1KMT2APOLBMAPT | |
| SCHEMBL3926770 | 0.85 | KCNA5 (0.49) | KCNA5MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL3915640 | 0.83 | KCNA5 (0.51) | KCNA5MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL3918373 | 0.83 | KCNA5 (0.52) | KCNA5MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL3916097 | 0.82 | KCNA5 (0.48) | KCNA5MEN1KMT2ARXFP1POLB | |
| SCHEMBL3914500 | 0.82 | KCNA5 (0.52) | KCNA5MEN1KMT2AATMMAPT | |
| SCHEMBL3915650 | 0.81 | KCNA5 (0.50) | KCNA5CYP1A2CYP2C9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035392-A1 | IMIDAZOLE KV1. 5 POTASSIUM CHANNEL INHIBITORS | Wyeth a Corporation of the State of Delaware (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007149874-A1 | IMIDAZOLIDINONE KV1.5 POTASSIUM CHANNEL INHIBITORS | WYETH (US) | 2007-12-27 | — | — | WO | disclosed |