Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL989130 | 0.85 | CCNT1 (0.45) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL3918312 | 0.78 | ROS1 (0.38) | L3MBTL1CSNK1EKDM4EMAPK1NPSR1 | |
| SCHEMBL3917686 | 0.74 | CCNT1 (0.44) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL3912533 | 0.74 | CCNA2 (0.44) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL13199646 | 0.71 | CCNT1 (0.46) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL1554639 | 0.71 | MAPK14 (0.54) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL5205411 | 0.71 | CCNT1 (0.44) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL13359305 | 0.71 | CCNA2 (0.42) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL3916904 | 0.70 | GRM5 (0.35) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL12680021 | 0.70 | CYP1A1 (0.43) | CCNT1CCNA2CDK2CDK9MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024353-A2 | PYRAZOLE COMPOUNDS | Pfizer Products Inc. (US) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007105058-A2 | PYRAZOLE COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-09-20 | — | — | WO | disclosed |