Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 12/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.69 |
| ▸ | MAPT | P10636 | 10/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.69 |
| ▸ | HPGD | P15428 | 4/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.69 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | USP2 | O75604 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1943038 | 0.99 | MEN1 (0.71) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL3918990 | 0.98 | MEN1 (0.69) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL3918992 | 0.88 | MEN1 (0.69) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL61629 | 0.83 | MEN1 (0.81) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL30195208 | 0.83 | MEN1 (1.00) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL61603 | 0.83 | MEN1 (1.00) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL23782005 | 0.82 | MEN1 (0.97) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL1942640 | 0.81 | MEN1 (0.69) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL31087879 | 0.81 | MEN1 (0.76) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL8112401 | 0.81 | MEN1 (0.76) | MEN1KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563907-B2 | Compounds based on polymethines | DYOMICS GMBH (DE) | 2009-07-21 | — | — | US | disclosed |
| US-20040260093-A1 | Compound, especially marker-dye on the basis of polymethines | DYOMICS GMBH (DE) | 2004-12-23 | — | — | US | disclosed |
| US-20030165942-A1 | Compound, especially marker-dye, on the basis of polymethines | DYOMICS GMBH (DE) | 2003-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030165942-A1 | Compound, especially marker-dye, on the basis of polymethines | MKI67, CYBA, IK | MEN1 2072/4885KMT2A 3198/4885MAPT 1322/4885 |
| US-20040260093-A1 | Compound, especially marker-dye on the basis of polymethines | MKI67, IK, CYBA | MEN1 2360/4885KMT2A 3470/4885MAPT 1262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.