Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.81 |
| ▸ | MAPT | P10636 | 10/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.81 |
| ▸ | HPGD | P15428 | 5/20 | 0.81 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.81 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.56 |
| ▸ | ATM | Q13315 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | USP2 | O75604 | 4/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11583563 | 0.92 | MEN1 (0.71) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL61603 | 0.90 | MEN1 (1.00) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL30195208 | 0.90 | MEN1 (1.00) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL23782005 | 0.89 | MEN1 (0.97) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL11627303 | 0.85 | KMT2A (0.72) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL11583737 | 0.85 | MEN1 (0.80) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL1943038 | 0.84 | MEN1 (0.71) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL1942640 | 0.83 | MEN1 (0.69) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL3918990 | 0.83 | MEN1 (0.69) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL3919002 | 0.83 | MEN1 (0.69) | MEN1KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129525-B2 | Long wavelength thiol-reactive fluorophores | BECTON DICKINSON AND COMPANY (US) | 2012-03-06 | — | — | US | disclosed |
| US-8129525-B2 | Long wavelength thiol-reactive fluorophores | BECTON DICKINSON AND COMPANY (US) | 2012-03-06 | — | — | US | disclosed |
| US-8071794-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON AND COMPANY (US) | 2011-12-06 | — | — | US | disclosed |
| US-8071794-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON AND COMPANY (US) | 2011-12-06 | — | — | US | disclosed |
| US-20110184168-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | BECTON, DICKINSON AND COMPANY (US) | 2011-07-28 | — | — | US | disclosed |
| US-20110184168-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | BECTON, DICKINSON AND COMPANY (US) | 2011-07-28 | — | — | US | disclosed |
| EP-2223971-A1 | Long wavelength thiol-reactive fluorophores | Becton, Dickinson & Company (US) | 2010-09-01 | — | — | EP | disclosed |
| US-7767821-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON & COMPANY (US) | 2010-08-03 | — | — | US | disclosed |
| US-7767821-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON & COMPANY (US) | 2010-08-03 | — | — | US | disclosed |
| US-20100003763-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | BECTON, DICKINSON AND COMPANY (US) | 2010-01-07 | — | — | US | disclosed |
| US-20100003763-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | BECTON, DICKINSON AND COMPANY (US) | 2010-01-07 | — | — | US | disclosed |
| US-7563891-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON & COMPANY (US) | 2009-07-21 | — | — | US | disclosed |
| US-7563891-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON & COMPANY (US) | 2009-07-21 | — | — | US | disclosed |
| EP-2036953-A2 | Long wavelength thiol-reactive fluorophores | Becton, Dickinson & Company (US) | 2009-03-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100003763-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | NUCB2, NDC1, NCBP1 | MEN1 4815/4885KMT2A 3702/4885MAPT 2743/4885 |
| US-20110184168-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | NUCB2, NDC1, NCBP1 | MEN1 4815/4885KMT2A 3702/4885MAPT 2743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.