Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2740855 | 1.00 | SIGMAR1 (0.52) | SIGMAR1EPHX1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL28482525 | 1.00 | SIGMAR1 (0.52) | SIGMAR1EPHX1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL28482705 | 1.00 | SIGMAR1 (0.52) | SIGMAR1EPHX1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL28484902 | 1.00 | SIGMAR1 (0.52) | SIGMAR1EPHX1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL28484903 | 1.00 | SIGMAR1 (0.52) | SIGMAR1EPHX1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL28484899 | 0.96 | SIGMAR1 (0.46) | SIGMAR1EPHX1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL6155359 | 0.79 | SIGMAR1 (0.58) | SIGMAR1EPHX1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL2740853 | 0.79 | SIGMAR1 (0.53) | SIGMAR1EPHX1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL6577782 | 0.79 | SIGMAR1 (0.49) | SIGMAR1EPHX1ALDH1A1CYP3A4TP53 | |
| SCHEMBL18465336 | 0.76 | SIGMAR1 (0.46) | SIGMAR1EPHX1SMN1; SMN2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026754-A2 | LIGHTENING AND/OR COLOURING AGENT COMPRISING CYCLIC UREA DERIVATIVES | Henkel AG & Co. KGaA (DE) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007137676-A2 | LIGHTENING AND/OR COLOURING AGENT COMPRISING CYCLIC UREA DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2007-12-06 | — | — | WO | disclosed |